| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | VIVO CAPITAL, LLC | 14,096,338 | 6,752,000 | 51.57% | ||
| 2 | FRANKLIN RESOURCES INC | 9,499,615 | 4,550,000 | 34.75% | ||
| 3 | VANGUARD GROUP INC | 1,933,747 | 927,000 | 7.08% | ||
| 4 | BAKER BROS. ADVISORS LP | 598,758 | 287,000 | 2.19% | ||
| 5 | Virtu KCG Holdings LLC | 503,418 | 241,000 | 1.84% | ||
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 323,967 | 155,000 | 1.18% | ||
| 7 | NORTHERN TRUST CORP | 92,518 | 44,000 | 0.34% | ||
| 8 | FIRST WILSHIRE SECURITIES MANAGEMENT INC | 58,027 | 28,000 | 0.21% | ||
| 9 | LPL Financial LLC | 40,000 | 19,000 | 0.15% | ||
| 10 | Moors & Cabot, Inc. | 40,000 | 19,000 | 0.15% | ||
| 11 | Bank of New York Mellon Corp | 27,495 | 13,000 | 0.10% | ||
| 12 | OPPENHEIMER & CO INC | 28,000 | 13,000 | 0.10% | ||
| 13 | GUGGENHEIM CAPITAL LLC | 22,718 | 11,000 | 0.08% | ||
| 14 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 22,100 | 11,000 | 0.08% | ||
| 15 | CITADEL ADVISORS LLC | 19,447 | 9,000 | 0.07% | ||
| 16 | COMMERCE BANK | 10,000 | 5,000 | 0.04% | ||
| 17 | TWO SIGMA SECURITIES, LLC | 11,385 | 5,000 | 0.04% | ||
| 18 | UBS Group AG | 5,064 | 2,000 | 0.02% | ||
| 19 | BlackRock Finance, Inc. | 3,675 | 2,000 | 0.02% | ||
| 20 | MORGAN STANLEY | 100 | 0 | 0.00% | ||
| 21 | CITIGROUP INC | 1,000 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
