| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BlackRock Finance, Inc. | 2,368,538 | 16,888,000 | 10.65% | ||
| 2 | CANADA PENSION PLAN INVESTMENT BOARD | 1,654,100 | 11,794,000 | 7.44% | ||
| 3 | WELLINGTON MANAGEMENT GROUP LLP | 1,572,026 | 11,209,000 | 7.07% | ||
| 4 | VANGUARD GROUP INC | 1,418,874 | 10,117,000 | 6.38% | ||
| 5 | FMR LLC | 1,336,034 | 9,526,000 | 6.01% | ||
| 6 | DIMENSIONAL FUND ADVISORS LP | 1,101,255 | 7,853,000 | 4.95% | ||
| 7 | Tekla Capital Management LLC | 1,004,322 | 7,161,000 | 4.51% | ||
| 8 | NORTHERN TRUST CORP | 886,765 | 6,323,000 | 3.99% | ||
| 9 | Numeric Investors LLC | 754,364 | 5,379,000 | 3.39% | ||
| 10 | STATE STREET CORP | 725,094 | 5,165,000 | 3.26% | ||
| 11 | Rock Springs Capital Management LP | 698,000 | 4,977,000 | 3.14% | ||
| 12 | EcoR1 Capital, LLC | 633,400 | 4,516,000 | 2.85% | ||
| 13 | EVENTIDE ASSET MANAGEMENT, LLC | 600,000 | 4,278,000 | 2.70% | ||
| 14 | MILLENNIUM MANAGEMENT LLC | 590,988 | 4,214,000 | 2.66% | ||
| 15 | DLD ASSET MANAGEMENT, LP | 570,000 | 4,059,000 | 2.56% | Put | |
| 16 | MORGAN STANLEY | 401,420 | 2,862,000 | 1.80% | ||
| 17 | Opaleye Management Inc. | 330,000 | 2,353,000 | 1.48% | ||
| 18 | GEODE CAPITAL MANAGEMENT, LLC | 321,676 | 2,293,000 | 1.45% | ||
| 19 | Rhenman & Partners Asset Management AB | 300,000 | 2,139,000 | 1.35% | ||
| 20 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 280,900 | 2,003,000 | 1.26% | Call | |
| 21 | Hudson Bay Capital Management LP | 274,685 | 1,959,000 | 1.24% | ||
| 22 | BALYASNY ASSET MANAGEMENT L.P. | 246,300 | 1,756,000 | 1.11% | ||
| 23 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 242,200 | 1,727,000 | 1.09% | ||
| 24 | DLD ASSET MANAGEMENT, LP | 230,000 | 1,640,000 | 1.03% | ||
| 25 | FEDERATED HERMES, INC. | 206,574 | 1,473,000 | 0.93% | ||
| 26 | Candriam S.C.A. | 201,000 | 1,433,000 | 0.90% | ||
| 27 | Bank of New York Mellon Corp | 194,144 | 1,384,000 | 0.87% | ||
| 28 | PDT Partners, LLC | 191,952 | 1,369,000 | 0.86% | ||
| 29 | Crestline Management, LP | 161,403 | 1,151,000 | 0.73% | ||
| 30 | RENAISSANCE TECHNOLOGIES LLC | 143,685 | 1,024,000 | 0.65% | ||
| 31 | D. E. Shaw & Co., Inc. | 130,320 | 930,000 | 0.59% | ||
| 32 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 129,681 | 925,000 | 0.58% | ||
| 33 | A.R.T. Advisors, LLC | 129,425 | 922,000 | 0.58% | ||
| 34 | GABELLI FUNDS LLC | 128,000 | 913,000 | 0.58% | ||
| 35 | ACADIAN ASSET MANAGEMENT LLC | 127,171 | 907,000 | 0.57% | ||
| 36 | DEUTSCHE BANK AG\ | 126,422 | 900,000 | 0.57% | ||
| 37 | JACOBS LEVY EQUITY MANAGEMENT, INC | 105,700 | 754,000 | 0.48% | ||
| 38 | TIAA CREF INVESTMENT MANAGEMENT LLC | 99,919 | 712,000 | 0.45% | ||
| 39 | BARCLAYS PLC | 97,397 | 694,000 | 0.44% | ||
| 40 | STRS OHIO | 81,000 | 577,000 | 0.36% | ||
| 41 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 79,800 | 569,000 | 0.36% | ||
| 42 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 78,300 | 558,000 | 0.35% | Put | |
| 43 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 69,595 | 496,000 | 0.31% | ||
| 44 | TEACHERS ADVISORS, LLC | 67,136 | 479,000 | 0.30% | ||
| 45 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 67,020 | 478,000 | 0.30% | ||
| 46 | DOW CHEMICAL CO /DE/ | 65,000 | 463,000 | 0.29% | ||
| 47 | BOOTHBAY FUND MANAGEMENT, LLC | 63,597 | 453,000 | 0.29% | ||
| 48 | PANAGORA ASSET MANAGEMENT INC | 62,746 | 447,000 | 0.28% | ||
| 49 | ALLIANCEBERNSTEIN L.P. | 59,200 | 422,000 | 0.27% | ||
| 50 | Squarepoint Ops LLC | 57,663 | 411,000 | 0.26% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
