| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | EVENTIDE ASSET MANAGEMENT, LLC | 225,000 | 3,143,000 | 1.43% | ||
| 52 | BOXER CAPITAL, LLC | 234,220 | 3,272,000 | 1.49% | ||
| 53 | HILLHOUSE INVESTMENT MANAGEMENT, LTD. | 245,449 | 3,429,000 | 1.56% | ||
| 54 | SPHERA FUNDS MANAGEMENT LTD. | 296,310 | 4,139,000 | 1.89% | ||
| 55 | Artal Group S.A. | 300,000 | 4,191,000 | 1.91% | ||
| 56 | Alyeska Investment Group, L.P. | 325,000 | 4,540,000 | 2.07% | ||
| 57 | ORBIMED ADVISORS LLC | 437,000 | 6,105,000 | 2.78% | ||
| 58 | JPMORGAN CHASE & CO | 439,070 | 6,134,000 | 2.80% | ||
| 59 | ArrowMark Colorado Holdings LLC | 466,427 | 6,516,000 | 2.97% | ||
| 60 | VANGUARD GROUP INC | 512,624 | 7,161,000 | 3.26% | ||
| 61 | MILLENNIUM MANAGEMENT LLC | 761,203 | 10,634,000 | 4.85% | ||
| 62 | JENNISON ASSOCIATES LLC | 953,862 | 13,325,000 | 6.07% | ||
| 63 | FMR LLC | 1,341,644 | 18,743,000 | 8.54% | ||
| 64 | BlackRock Finance, Inc. | 1,889,109 | 26,390,000 | 12.03% | ||
| 65 | MPM ASSET MANAGEMENT LLC | 2,168,691 | 30,297,000 | 13.81% | ||
| 66 | WELLINGTON MANAGEMENT GROUP LLP | 3,076,367 | 42,977,000 | 19.59% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.