| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | SABBY MANAGEMENT, LLC | 2,365,763 | 2,371,000 | 40.92% | ||
| 2 | Cormorant Asset Management, LP | 1,002,516 | 1,013,000 | 17.48% | SH | |
| 3 | PERCEPTIVE ADVISORS LLC | 837,886 | 837,000 | 14.45% | ||
| 4 | Avoro Capital Advisors LLC | 683,531 | 684,000 | 11.81% | ||
| 5 | VANGUARD GROUP INC | 282,740 | 285,000 | 4.92% | ||
| 6 | MARSHALL WACE NORTH AMERICA, L.P. | 261,800 | 262,000 | 4.52% | ||
| 7 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 138,000 | 139,000 | 2.40% | ||
| 8 | PANAGORA ASSET MANAGEMENT INC | 64,829 | 65,000 | 1.12% | ||
| 9 | BlackRock Finance, Inc. | 32,266 | 32,000 | 0.55% | ||
| 10 | MILLENNIUM MANAGEMENT LLC | 31,321 | 31,000 | 0.54% | ||
| 11 | ACUTA CAPITAL PARTNERS, LLC | 29,082 | 29,000 | 0.50% | ||
| 12 | MORGAN STANLEY | 21,211 | 21,000 | 0.36% | ||
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 11,165 | 11,000 | 0.19% | ||
| 14 | WELLS FARGO & COMPANY/MN | 10,100 | 10,000 | 0.17% | ||
| 15 | Advisory Services Network, LLC | 2,000 | 2,000 | 0.03% | ||
| 16 | UBS Group AG | 1,950 | 2,000 | 0.03% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.