| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | VANGUARD GROUP INC | 128,102 | 3,202,000 | 0.95% | ||
| 52 | Alyeska Investment Group, L.P. | 149,651 | 3,741,000 | 1.12% | ||
| 53 | GEODE CAPITAL MANAGEMENT, LLC | 164,904 | 4,122,000 | 1.23% | ||
| 54 | DEERFIELD MANAGEMENT COMPANY, L.P. | 216,761 | 5,419,000 | 1.62% | ||
| 55 | YALE UNIVERSITY | 250,000 | 6,250,000 | 1.86% | ||
| 56 | Rock Springs Capital Management LP | 307,000 | 7,675,000 | 2.29% | ||
| 57 | EMERALD MUTUAL FUND ADVISERS TRUST | 352,560 | 8,814,000 | 2.63% | ||
| 58 | WELLINGTON MANAGEMENT GROUP LLP | 356,107 | 8,904,000 | 2.65% | ||
| 59 | STIFEL FINANCIAL CORP | 415,200 | 10,381,000 | 3.09% | ||
| 60 | ALLIANCEBERNSTEIN L.P. | 435,209 | 10,880,000 | 3.24% | ||
| 61 | PRICE T ROWE ASSOCIATES INC /MD/ | 496,128 | 12,403,000 | 3.70% | ||
| 62 | EMERALD ADVISERS, LLC | 497,880 | 12,447,000 | 3.71% | ||
| 63 | JPMORGAN CHASE & CO | 593,225 | 14,831,000 | 4.42% | ||
| 64 | JANUS HENDERSON GROUP PLC | 645,743 | 16,144,000 | 4.81% | ||
| 65 | Knoll Capital Management, LLC | 807,224 | 20,181,000 | 6.02% | ||
| 66 | BlackRock Finance, Inc. | 1,020,932 | 25,523,000 | 7.61% | ||
| 67 | FMR LLC | 1,035,523 | 25,888,000 | 7.72% | ||
| 68 | VHCP MANAGEMENT II, LLC | 1,664,300 | 37,930,000 | 11.31% | ||
| 69 | RA CAPITAL MANAGEMENT, L.P. | 2,448,350 | 61,209,000 | 18.25% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
