| 1 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
9,488,461 |
33,210,000 |
19.03% |
|
|
| 2 |
BlackRock Institutional Trust Company, N.A. |
4,061,785 |
14,216,000 |
8.14% |
|
|
| 3 |
VANGUARD GROUP INC |
3,770,476 |
13,196,000 |
7.56% |
|
|
| 4 |
ORBIMED ADVISORS LLC |
3,213,900 |
11,249,000 |
6.44% |
|
|
| 5 |
BlackRock Fund Advisors |
3,172,823 |
11,105,000 |
6.36% |
|
|
| 6 |
Broadfin Capital, LLC |
2,300,000 |
8,050,000 |
4.61% |
|
|
| 7 |
MILLENNIUM MANAGEMENT LLC |
2,246,616 |
7,863,000 |
4.50% |
|
|
| 8 |
STATE STREET CORP |
2,003,302 |
7,012,000 |
4.02% |
|
|
| 9 |
Allianz Asset Management GmbH |
1,835,234 |
6,423,000 |
3.68% |
|
|
| 10 |
WILLIAM HARRIS INVESTORS INC |
1,513,735 |
5,298,000 |
3.04% |
|
|
| 11 |
KINGDON CAPITAL MANAGEMENT, L.L.C. |
1,490,738 |
5,203,000 |
2.98% |
|
|
| 12 |
NORTHERN TRUST CORP |
1,468,000 |
5,137,000 |
2.94% |
|
|
| 13 |
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
1,127,596 |
3,947,000 |
2.26% |
|
|
| 14 |
PUTNAM INVESTMENTS LLC |
1,072,139 |
3,753,000 |
2.15% |
|
|
| 15 |
J. Goldman & Co LP |
973,572 |
3,408,000 |
1.95% |
|
|
| 16 |
Bank of New York Mellon Corp |
922,742 |
3,230,000 |
1.85% |
|
|
| 17 |
ASHFORD CAPITAL MANAGEMENT INC |
860,575 |
3,012,000 |
1.73% |
|
|
| 18 |
GEODE CAPITAL MANAGEMENT, LLC |
635,235 |
2,223,000 |
1.27% |
|
|
| 19 |
Park West Asset Management LLC |
500,000 |
1,750,000 |
1.00% |
|
|
| 20 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
437,325 |
1,531,000 |
0.88% |
|
|
| 21 |
AVENIR CORP |
338,735 |
1,186,000 |
0.68% |
|
|
| 22 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
362,300 |
1,184,000 |
0.68% |
|
|
| 23 |
CADENCE CAPITAL MANAGEMENT LLC |
337,592 |
1,182,000 |
0.68% |
|
|
| 24 |
BlackRock Investment Management, LLC |
312,236 |
1,093,000 |
0.63% |
|
|
| 25 |
MARINER INVESTMENT GROUP LLC |
296,477 |
1,038,000 |
0.59% |
|
|
| 26 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
290,174 |
1,016,000 |
0.58% |
|
|
| 27 |
CIBC Private Wealth Group LLC |
277,000 |
1,011,000 |
0.58% |
|
|
| 28 |
Ghost Tree Capital, LLC |
250,000 |
875,000 |
0.50% |
|
|
| 29 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
242,700 |
849,000 |
0.49% |
Call |
|
| 30 |
ALLIANCEBERNSTEIN L.P. |
221,389 |
775,000 |
0.44% |
|
|
| 31 |
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
220,000 |
770,000 |
0.44% |
|
|
| 32 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
204,035 |
714,000 |
0.41% |
|
|
| 33 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
197,432 |
691,000 |
0.40% |
|
|
| 34 |
CREDIT SUISSE AG/ |
178,639 |
625,000 |
0.36% |
|
|
| 35 |
TEACHERS ADVISORS, LLC |
162,222 |
568,000 |
0.33% |
|
|
| 36 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
159,600 |
559,000 |
0.32% |
Put |
|
| 37 |
WELLS FARGO & COMPANY/MN |
151,500 |
530,000 |
0.30% |
|
|
| 38 |
NATIONAL PLANNING CORP |
140,850 |
514,000 |
0.29% |
|
|
| 39 |
Swiss National Bank |
137,300 |
481,000 |
0.28% |
|
|
| 40 |
CITIGROUP INC |
120,949 |
424,000 |
0.24% |
|
|
| 41 |
ProShare Advisors LLC |
114,149 |
400,000 |
0.23% |
|
|
| 42 |
GOLDMAN SACHS GROUP INC |
98,542 |
345,000 |
0.20% |
|
|
| 43 |
Coe Capital Management, LLC |
97,475 |
341,000 |
0.20% |
|
|
| 44 |
IRIDIAN ASSET MANAGEMENT LLC/CT |
96,270 |
337,000 |
0.19% |
|
|
| 45 |
RHUMBLINE ADVISERS |
94,965 |
332,000 |
0.19% |
|
|
| 46 |
VOYA INVESTMENT MANAGEMENT LLC |
93,600 |
328,000 |
0.19% |
|
|
| 47 |
AQR CAPITAL MANAGEMENT LLC |
93,631 |
328,000 |
0.19% |
|
|
| 48 |
METROPOLITAN LIFE INSURANCE CO/NY |
92,043 |
322,000 |
0.18% |
|
|
| 49 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
88,254 |
309,000 |
0.18% |
|
|
| 50 |
Commonwealth Equity Services, Inc |
83,700 |
293,000 |
0.17% |
|
|
