| 1 |
NEA Management Company, LLC |
3,945,191 |
57,126,000 |
31.50% |
|
|
| 2 |
MPM ASSET MANAGEMENT LLC |
1,776,692 |
25,727,000 |
14.19% |
|
|
| 3 |
Redmile Group, LLC |
1,751,518 |
25,534,000 |
14.08% |
|
|
| 4 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
1,532,531 |
22,191,000 |
12.24% |
|
|
| 5 |
FMR LLC |
1,480,000 |
21,430,000 |
11.82% |
|
|
| 6 |
WELLINGTON MANAGEMENT GROUP LLP |
631,745 |
9,148,000 |
5.04% |
|
|
| 7 |
STIFEL FINANCIAL CORP |
331,262 |
5,158,000 |
2.84% |
|
|
| 8 |
BlackRock Fund Advisors |
175,553 |
2,542,000 |
1.40% |
|
|
| 9 |
DRIEHAUS CAPITAL MANAGEMENT LLC |
127,034 |
1,839,000 |
1.01% |
|
|
| 10 |
JPMORGAN CHASE & CO |
120,500 |
1,744,000 |
0.96% |
|
|
| 11 |
Allianz Asset Management GmbH |
77,200 |
1,118,000 |
0.62% |
|
|
| 12 |
NORTHERN TRUST CORP |
73,583 |
1,065,000 |
0.59% |
|
|
| 13 |
BlackRock Institutional Trust Company, N.A. |
64,065 |
928,000 |
0.51% |
|
|
| 14 |
VANGUARD GROUP INC |
60,558 |
877,000 |
0.48% |
|
|
| 15 |
UNITED SERVICES AUTOMOBILE ASSOCIATION |
58,800 |
851,000 |
0.47% |
|
|
| 16 |
GOLDMAN SACHS GROUP INC |
45,976 |
666,000 |
0.37% |
|
|
| 17 |
GEODE CAPITAL MANAGEMENT, LLC |
31,908 |
462,000 |
0.25% |
|
|
| 18 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
30,100 |
436,000 |
0.24% |
|
|
| 19 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
26,399 |
382,000 |
0.21% |
|
|
| 20 |
Bank of New York Mellon Corp |
25,880 |
374,000 |
0.21% |
|
|
| 21 |
STATE STREET CORP |
21,771 |
315,000 |
0.17% |
|
|
| 22 |
BlackRock Investment Management, LLC |
21,760 |
315,000 |
0.17% |
|
|
| 23 |
MILLENNIUM MANAGEMENT LLC |
17,744 |
257,000 |
0.14% |
|
|
| 24 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
13,678 |
198,000 |
0.11% |
|
|
| 25 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
10,900 |
158,000 |
0.09% |
|
|
| 26 |
TEACHERS ADVISORS, LLC |
10,427 |
151,000 |
0.08% |
|
|
| 27 |
Tower Research Capital LLC (TRC) |
7,050 |
102,000 |
0.06% |
|
|
| 28 |
Nationwide Fund Advisors |
5,712 |
83,000 |
0.05% |
|
|
| 29 |
AMERICAN INTERNATIONAL GROUP, INC. |
4,857 |
70,329 |
0.04% |
|
|
| 30 |
BLACKROCK ADVISORS LLC |
3,156 |
46,000 |
0.03% |
|
|
| 31 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
1,869 |
27,000 |
0.01% |
|
|
| 32 |
MORGAN STANLEY |
883 |
13,000 |
0.01% |
|
|
| 33 |
ALLIANCEBERNSTEIN L.P. |
500 |
7,000 |
0.00% |
|
|
| 34 |
BNP PARIBAS FINANCIAL MARKETS |
422 |
6,111 |
0.00% |
|
|
| 35 |
WELLS FARGO & COMPANY/MN |
343 |
5,000 |
0.00% |
|
|
| 36 |
CITIGROUP INC |
309 |
5,000 |
0.00% |
|
|
| 37 |
UBS AG |
298 |
4,000 |
0.00% |
|
|
| 38 |
BARCLAYS PLC |
77 |
1,000 |
0.00% |
|
|
| 39 |
MSI Financial Services Inc |
100 |
1,000 |
0.00% |
|
|
| 40 |
BANK OF AMERICA CORP /DE/ |
9 |
0 |
0.00% |
|
|
| 41 |
STRS OHIO |
0 |
0 |
0.00% |
|
|
| 42 |
DEUTSCHE BANK AG\ |
69 |
0 |
0.00% |
|
|
