| 1 |
BLAIR WILLIAM & CO/IL |
5,755,768 |
2,257,000 |
18.32% |
|
|
| 2 |
Sio Capital Management, LLC |
5,386,213 |
2,112,000 |
17.14% |
|
|
| 3 |
Granahan Investment Management, LLC |
2,661,969 |
1,044,000 |
8.47% |
|
|
| 4 |
VANGUARD GROUP INC |
2,353,673 |
923,000 |
7.49% |
|
|
| 5 |
SABBY MANAGEMENT, LLC |
2,225,081 |
872,000 |
7.08% |
|
|
| 6 |
FMR LLC |
2,000,125 |
784,000 |
6.36% |
|
|
| 7 |
KENNEDY CAPITAL MANAGEMENT LLC |
1,479,580 |
580,000 |
4.71% |
|
|
| 8 |
ACUTA CAPITAL PARTNERS, LLC |
1,456,884 |
571,000 |
4.64% |
|
|
| 9 |
NORTHPOINTE CAPITAL LLC |
1,273,444 |
499,000 |
4.05% |
|
|
| 10 |
DEUTSCHE BANK AG\ |
1,165,087 |
456,000 |
3.70% |
|
|
| 11 |
PERCEPTIVE ADVISORS LLC |
707,566 |
277,000 |
2.25% |
|
|
| 12 |
DAFNA Capital Management LLC |
600,000 |
235,000 |
1.91% |
|
|
| 13 |
UNITED SERVICES AUTOMOBILE ASSOCIATION |
534,715 |
210,000 |
1.70% |
|
|
| 14 |
Anson Funds Management LP |
454,752 |
178,000 |
1.44% |
|
|
| 15 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
412,563 |
162,000 |
1.32% |
|
|
| 16 |
GEODE CAPITAL MANAGEMENT, LLC |
405,259 |
158,000 |
1.28% |
|
|
| 17 |
D. E. Shaw & Co., Inc. |
349,991 |
137,000 |
1.11% |
|
|
| 18 |
RENAISSANCE TECHNOLOGIES LLC |
284,462 |
112,000 |
0.91% |
|
|
| 19 |
BlackRock Fund Advisors |
284,188 |
111,000 |
0.90% |
|
|
| 20 |
CITADEL ADVISORS LLC |
194,833 |
76,000 |
0.62% |
|
|
| 21 |
Virtu KCG Holdings LLC |
194,647 |
76,000 |
0.62% |
|
|
| 22 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
224,322 |
69,000 |
0.56% |
|
|
| 23 |
NORTHERN TRUST CORP |
115,712 |
45,000 |
0.37% |
|
|
| 24 |
NSB Advisors LLC |
114,200 |
45,000 |
0.37% |
|
|
| 25 |
TWO SIGMA INVESTMENTS, LP |
76,233 |
30,000 |
0.24% |
|
|
| 26 |
JW Asset Management, LLC |
76,995 |
30,000 |
0.24% |
|
|
| 27 |
Bank of New York Mellon Corp |
75,964 |
30,000 |
0.24% |
|
|
| 28 |
MILLENNIUM MANAGEMENT LLC |
71,102 |
28,000 |
0.23% |
|
|
| 29 |
UBS Group AG |
56,261 |
22,000 |
0.18% |
|
|
| 30 |
GOLDMAN SACHS GROUP INC |
56,632 |
22,000 |
0.18% |
|
|
| 31 |
OXFORD ASSET MANAGEMENT LLP |
54,228 |
21,000 |
0.17% |
|
|
| 32 |
Connor, Clark & Lunn Investment Management Ltd. |
49,100 |
19,000 |
0.15% |
|
|
| 33 |
PERKINS CAPITAL MANAGEMENT INC |
38,000 |
15,000 |
0.12% |
|
|
| 34 |
GOULD ASSET MANAGEMENT LLC /CA/ |
30,000 |
12,000 |
0.10% |
|
|
| 35 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
30,500 |
12,000 |
0.10% |
|
|
| 36 |
Commonwealth Equity Services, Inc |
25,700 |
10,000 |
0.08% |
|
|
| 37 |
Onex Canada Asset Management Inc. |
25,000 |
10,000 |
0.08% |
|
|
| 38 |
STATE STREET CORP |
24,900 |
10,000 |
0.08% |
|
|
| 39 |
BLACKROCK ADVISORS LLC |
18,468 |
7,000 |
0.06% |
|
|
| 40 |
LPL Financial LLC |
16,000 |
6,000 |
0.05% |
|
|
| 41 |
MORGAN STANLEY |
15,461 |
6,000 |
0.05% |
|
|
| 42 |
BlackRock Investment Management, LLC |
15,655 |
6,000 |
0.05% |
|
|
| 43 |
ROYAL BANK OF CANADA |
16,500 |
6,000 |
0.05% |
|
|
| 44 |
GROUP ONE TRADING LLC |
13,673 |
5,000 |
0.04% |
|
|
| 45 |
GUGGENHEIM CAPITAL LLC |
12,542 |
5,000 |
0.04% |
|
|
| 46 |
Salient Capital Advisors, LLC |
11,000 |
4,000 |
0.03% |
|
|
| 47 |
UBS Group AG |
8,000 |
3,000 |
0.02% |
Call |
|
| 48 |
STANCORP INVESTMENT ADVISERS INC |
7,143 |
3,000 |
0.02% |
|
|
| 49 |
BANK OF MONTREAL /CAN/ |
6,000 |
2,000 |
0.02% |
|
|
| 50 |
PNC FINANCIAL SERVICES GROUP, INC. |
3,000 |
2,000 |
0.02% |
|
|
