| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | MAVERICK CAPITAL LTD | 7,061,034 | 41,236,000 | 17.94% | ||
| 2 | ORACLE INVESTMENT MANAGEMENT INC | 3,284,796 | 19,183,000 | 8.35% | ||
| 3 | DEERFIELD MANAGEMENT COMPANY, L.P. | 3,048,310 | 17,802,000 | 7.75% | ||
| 4 | BLACKROCK ADVISORS LLC | 2,786,024 | 16,270,000 | 7.08% | ||
| 5 | BlackRock Fund Advisors | 2,573,649 | 15,030,000 | 6.54% | ||
| 6 | Blackstone Inc. | 2,411,556 | 14,083,000 | 6.13% | ||
| 7 | MILLENNIUM MANAGEMENT LLC | 2,168,907 | 12,666,000 | 5.51% | ||
| 8 | Consonance Capital Management LP | 2,002,971 | 11,697,000 | 5.09% | ||
| 9 | VANGUARD GROUP INC | 1,817,658 | 10,616,000 | 4.62% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 1,141,818 | 6,668,000 | 2.90% | ||
| 11 | Numeric Investors LLC | 932,517 | 5,446,000 | 2.37% | ||
| 12 | STATE STREET CORP | 804,010 | 4,693,000 | 2.04% | ||
| 13 | NORTHERN TRUST CORP | 615,537 | 3,594,000 | 1.56% | ||
| 14 | BlackRock Group LTD | 551,020 | 3,218,000 | 1.40% | ||
| 15 | PANAGORA ASSET MANAGEMENT INC | 530,859 | 3,100,000 | 1.35% | ||
| 16 | FULLER & THALER ASSET MANAGEMENT, INC. | 492,539 | 2,876,000 | 1.25% | ||
| 17 | LORD, ABBETT & CO. LLC | 471,153 | 2,751,000 | 1.20% | ||
| 18 | MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 433,875 | 2,534,000 | 1.10% | ||
| 19 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 275,050 | 2,272,000 | 0.99% | ||
| 20 | BlackRock Investment Management, LLC | 373,329 | 2,180,000 | 0.95% | ||
| 21 | GEODE CAPITAL MANAGEMENT, LLC | 365,097 | 2,132,000 | 0.93% | ||
| 22 | D. E. Shaw & Co., Inc. | 353,144 | 2,063,000 | 0.90% | ||
| 23 | Bank of New York Mellon Corp | 350,924 | 2,049,000 | 0.89% | ||
| 24 | DIMENSIONAL FUND ADVISORS LP | 335,413 | 1,959,000 | 0.85% | ||
| 25 | OXFORD ASSET MANAGEMENT LLP | 302,982 | 1,769,000 | 0.77% | ||
| 26 | ING GROEP NV | 250,000 | 1,460,000 | 0.64% | ||
| 27 | Spark Investment Management LLC | 236,700 | 1,379,000 | 0.60% | ||
| 28 | TIAA CREF INVESTMENT MANAGEMENT LLC | 203,883 | 1,191,000 | 0.52% | ||
| 29 | DEUTSCHE BANK AG\ | 187,269 | 1,091,000 | 0.47% | ||
| 30 | ESSEX INVESTMENT MANAGEMENT CO LLC | 150,144 | 877,000 | 0.38% | ||
| 31 | Iguana Healthcare Management, LLC | 150,000 | 876,000 | 0.38% | ||
| 32 | JPMORGAN CHASE & CO | 140,355 | 819,000 | 0.36% | ||
| 33 | GSA CAPITAL PARTNERS LLP | 138,983 | 812,000 | 0.35% | ||
| 34 | STRS OHIO | 129,300 | 755,000 | 0.33% | ||
| 35 | RENAISSANCE TECHNOLOGIES LLC | 125,200 | 731,000 | 0.32% | ||
| 36 | Connor, Clark & Lunn Investment Management Ltd. | 117,978 | 689,000 | 0.30% | ||
| 37 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 111,004 | 648,000 | 0.28% | ||
| 38 | Weiss Multi-Strategy Advisers LLC | 110,000 | 642,000 | 0.28% | ||
| 39 | AQR CAPITAL MANAGEMENT LLC | 109,654 | 641,000 | 0.28% | ||
| 40 | ALLIANCEBERNSTEIN L.P. | 90,900 | 531,000 | 0.23% | ||
| 41 | Compagnie Lombard Odier SCmA | 88,000 | 514,000 | 0.22% | ||
| 42 | Trellus Management Company, LLC | 87,400 | 510,000 | 0.22% | ||
| 43 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 87,004 | 508,000 | 0.22% | ||
| 44 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 85,600 | 500,000 | 0.22% | ||
| 45 | TEACHERS ADVISORS, LLC | 83,514 | 488,000 | 0.21% | ||
| 46 | RHUMBLINE ADVISERS | 77,026 | 450,000 | 0.20% | ||
| 47 | GOLDMAN SACHS GROUP INC | 71,721 | 419,000 | 0.18% | ||
| 48 | ProShare Advisors LLC | 70,673 | 413,000 | 0.18% | ||
| 49 | CREDIT SUISSE AG/ | 70,465 | 411,000 | 0.18% | ||
| 50 | Swiss National Bank | 48,000 | 280,000 | 0.12% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
