| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PRICE T ROWE ASSOCIATES INC /MD/ | 27,941,721 | 4,369,806,000 | 12.91% | ||
| 2 | Capital Research Global Investors | 27,407,884 | 4,286,319,000 | 12.66% | ||
| 3 | FMR LLC | 14,520,601 | 2,270,877,000 | 6.71% | ||
| 4 | VANGUARD GROUP INC | 12,721,686 | 1,989,545,000 | 5.88% | ||
| 5 | JENNISON ASSOCIATES LLC | 6,864,993 | 1,073,616,000 | 3.17% | ||
| 6 | BAKER BROS. ADVISORS LP | 6,542,599 | 1,023,197,000 | 3.02% | ||
| 7 | SANDS CAPITAL MANAGEMENT, LLC | 6,379,857 | 997,746,000 | 2.95% | ||
| 8 | WELLS FARGO & COMPANY/MN | 6,235,817 | 975,221,000 | 2.88% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 5,587,151 | 873,775,000 | 2.58% | ||
| 10 | AMERIPRISE FINANCIAL INC | 5,487,005 | 858,002,000 | 2.53% | ||
| 11 | JPMORGAN CHASE & CO | 4,774,649 | 746,707,000 | 2.21% | ||
| 12 | BlackRock Fund Advisors | 4,743,223 | 741,793,000 | 2.19% | ||
| 13 | WADDELL & REED FINANCIAL INC | 3,456,687 | 540,591,000 | 1.60% | ||
| 14 | Invesco Ltd. | 3,228,731 | 504,940,000 | 1.49% | ||
| 15 | Winslow Capital Management, LLC | 3,211,156 | 502,192,000 | 1.48% | ||
| 16 | NORTHERN TRUST CORP | 2,785,792 | 435,671,000 | 1.29% | ||
| 17 | Bank of New York Mellon Corp | 2,632,000 | 411,813,000 | 1.22% | ||
| 18 | BlackRock Group LTD | 2,447,411 | 382,752,000 | 1.13% | ||
| 19 | BANK OF AMERICA CORP /DE/ | 2,316,590 | 362,292,000 | 1.07% | ||
| 20 | ORBIMED ADVISORS LLC | 2,226,600 | 348,218,000 | 1.03% | ||
| 21 | AMERICAN CENTURY COMPANIES INC | 2,108,989 | 329,825,000 | 0.97% | ||
| 22 | TIAA CREF INVESTMENT MANAGEMENT LLC | 2,054,151 | 321,249,000 | 0.95% | ||
| 23 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 1,959,177 | 306,395,000 | 0.91% | ||
| 24 | BROWN ADVISORY INC | 1,897,868 | 296,863,000 | 0.88% | ||
| 25 | GEODE CAPITAL MANAGEMENT, LLC | 1,787,966 | 279,071,000 | 0.82% | ||
| 26 | NORGES BANK | 1,672,300 | 261,531,000 | 0.77% | ||
| 27 | BLACKROCK ADVISORS LLC | 1,503,426 | 235,121,000 | 0.69% | ||
| 28 | DSM CAPITAL PARTNERS LLC | 1,247,387 | 195,078,000 | 0.58% | ||
| 29 | Temasek Holdings (Private) Ltd | 1,226,630 | 191,833,000 | 0.57% | ||
| 30 | GOLDMAN SACHS GROUP INC | 1,144,170 | 178,937,000 | 0.53% | ||
| 31 | TCW GROUP INC | 1,104,944 | 172,802,000 | 0.51% | ||
| 32 | BB BIOTECH AG | 1,034,428 | 161,774,000 | 0.48% | ||
| 33 | GENERAL ELECTRIC CO | 929,904 | 145,428,000 | 0.43% | ||
| 34 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 916,925 | 143,399,000 | 0.42% | ||
| 35 | Legal & General Group Plc | 896,428 | 140,191,000 | 0.41% | ||
| 36 | AXA S.A. | 883,834 | 138,222,000 | 0.41% | ||
| 37 | FIRST TRUST ADVISORS LP | 811,139 | 126,854,000 | 0.37% | ||
| 38 | Allianz Asset Management GmbH | 792,043 | 123,867,000 | 0.37% | ||
| 39 | JANUS HENDERSON INVESTORS US LLC | 788,213 | 123,268,000 | 0.36% | ||
| 40 | ALKEON CAPITAL MANAGEMENT LLC | 686,870 | 113,183,000 | 0.33% | ||
| 41 | SECTORAL ASSET MANAGEMENT INC | 721,593 | 112,850,000 | 0.33% | ||
| 42 | BlackRock Finance, Inc. | 718,729 | 112,402,000 | 0.33% | ||
| 43 | BlackRock Investment Management, LLC | 716,116 | 111,993,000 | 0.33% | ||
| 44 | THRIVENT FINANCIAL FOR LUTHERANS | 705,210 | 110,288,000 | 0.33% | ||
| 45 | RENAISSANCE TECHNOLOGIES LLC | 689,542 | 107,837,000 | 0.32% | ||
| 46 | MORGAN STANLEY | 673,378 | 105,309,000 | 0.31% | ||
| 47 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 668,800 | 104,594,000 | 0.31% | Put | |
| 48 | NEW YORK STATE COMMON RETIREMENT FUND | 662,534 | 103,614,000 | 0.31% | ||
| 49 | DEUTSCHE BANK AG\ | 645,660 | 100,968,000 | 0.30% | ||
| 50 | Tekla Capital Management LLC | 636,805 | 99,590,000 | 0.29% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
