| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | MPM ASSET MANAGEMENT LLC | 2,788,165 | 51,748,000 | 13.06% | ||
| 2 | JENNISON ASSOCIATES LLC | 1,907,857 | 35,410,000 | 8.94% | ||
| 3 | FRANKLIN RESOURCES INC | 1,593,157 | 29,569,000 | 7.46% | ||
| 4 | WELLINGTON MANAGEMENT GROUP LLP | 1,281,335 | 23,782,000 | 6.00% | ||
| 5 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,275,000 | 23,664,000 | 5.97% | ||
| 6 | ALLIANCEBERNSTEIN L.P. | 982,900 | 18,243,000 | 4.60% | ||
| 7 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 828,200 | 15,371,392 | 3.88% | ||
| 8 | DEERFIELD MANAGEMENT COMPANY, L.P. | 788,904 | 14,642,000 | 3.70% | ||
| 9 | JPMORGAN CHASE & CO | 744,650 | 13,821,000 | 3.49% | ||
| 10 | Broadfin Capital, LLC | 667,435 | 12,388,000 | 3.13% | ||
| 11 | MARXE AUSTIN W & GREENHOUSE DAVID M | 600,000 | 11,136,000 | 2.81% | ||
| 12 | RS INVESTMENT MANAGEMENT CO LLC | 578,900 | 10,744,000 | 2.71% | ||
| 13 | VANGUARD GROUP INC | 495,365 | 9,195,000 | 2.32% | ||
| 14 | WADDELL & REED FINANCIAL INC | 456,200 | 8,467,000 | 2.14% | ||
| 15 | BLAIR WILLIAM & CO/IL | 421,135 | 7,816,000 | 1.97% | ||
| 16 | CHARTWELL INVESTMENT PARTNERS/PA | 401,395 | 7,450,000 | 1.88% | ||
| 17 | D. E. Shaw & Co., Inc. | 352,068 | 6,534,000 | 1.65% | ||
| 18 | EAGLE ASSET MANAGEMENT INC | 349,048 | 6,478,000 | 1.64% | ||
| 19 | DRIEHAUS CAPITAL MANAGEMENT LLC | 341,530 | 6,339,000 | 1.60% | ||
| 20 | FMR LLC | 375,000 | 6,264,000 | 1.58% | ||
| 21 | GOLDMAN SACHS GROUP INC | 318,392 | 5,909,000 | 1.49% | ||
| 22 | BlackRock Institutional Trust Company, N.A. | 315,250 | 5,851,000 | 1.48% | ||
| 23 | FRED ALGER MANAGEMENT, LLC | 289,344 | 5,370,000 | 1.36% | ||
| 24 | OppenheimerFunds, Inc. | 282,292 | 5,240,000 | 1.32% | ||
| 25 | PRINCIPAL FINANCIAL GROUP INC | 254,500 | 4,724,000 | 1.19% | ||
| 26 | LAZARD ASSET MANAGEMENT LLC | 249,459 | 4,629,000 | 1.17% | ||
| 27 | Nicholas Investment Partners, LP | 241,706 | 4,486,000 | 1.13% | ||
| 28 | HIGHLAND CAPITAL MANAGEMENT LP | 229,004 | 4,250,000 | 1.07% | ||
| 29 | BlackRock Fund Advisors | 225,815 | 4,191,000 | 1.06% | ||
| 30 | Visium Asset Management, LP | 155,236 | 2,882,000 | 0.73% | ||
| 31 | Hutchin Hill Capital, LP | 150,000 | 2,784,000 | 0.70% | ||
| 32 | Grandeur Peak Global Advisors, LLC | 130,100 | 2,415,000 | 0.61% | ||
| 33 | STATE STREET CORP | 124,658 | 2,315,000 | 0.58% | ||
| 34 | NORTHERN TRUST CORP | 110,267 | 2,046,000 | 0.52% | ||
| 35 | CREDIT SUISSE AG/ | 109,940 | 2,040,000 | 0.51% | ||
| 36 | MILLENNIUM MANAGEMENT LLC | 100,242 | 1,860,000 | 0.47% | ||
| 37 | GEODE CAPITAL MANAGEMENT, LLC | 94,416 | 1,752,000 | 0.44% | ||
| 38 | Bank of New York Mellon Corp | 81,829 | 1,519,000 | 0.38% | ||
| 39 | Alyeska Investment Group, L.P. | 80,893 | 1,501,000 | 0.38% | ||
| 40 | WALL STREET ASSOCIATES | 75,297 | 1,398,000 | 0.35% | ||
| 41 | Creative Planning | 52,269 | 970,000 | 0.24% | ||
| 42 | First Light Asset Management, LLC | 49,263 | 914,000 | 0.23% | ||
| 43 | DEUTSCHE BANK AG\ | 35,490 | 657,000 | 0.17% | ||
| 44 | Mariner, LLC | 29,329 | 544,000 | 0.14% | ||
| 45 | BANK OF MONTREAL /CAN/ | 28,990 | 538,000 | 0.14% | ||
| 46 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 37,670 | 537,000 | 0.14% | ||
| 47 | Weiss Multi-Strategy Advisers LLC | 25,000 | 464,000 | 0.12% | ||
| 48 | BlackRock Investment Management, LLC | 22,803 | 423,000 | 0.11% | ||
| 49 | TIAA CREF INVESTMENT MANAGEMENT LLC | 22,460 | 417,000 | 0.11% | ||
| 50 | RAYMOND JAMES & ASSOCIATES | 21,800 | 405,000 | 0.10% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
