| 1 |
Novo Holdings A/S |
1,280,185 |
9,755,000 |
34.30% |
|
|
| 2 |
FMR LLC |
673,461 |
5,132,000 |
18.05% |
|
|
| 3 |
PUTNAM INVESTMENTS LLC |
575,692 |
4,386,000 |
15.42% |
|
|
| 4 |
BLACKROCK ADVISORS LLC |
463,200 |
3,530,000 |
12.41% |
|
|
| 5 |
Cormorant Asset Management, LP |
201,000 |
1,532,000 |
5.39% |
|
|
| 6 |
BlackRock Group LTD |
171,600 |
1,308,000 |
4.60% |
|
|
| 7 |
Alyeska Investment Group, L.P. |
114,113 |
870,000 |
3.06% |
|
|
| 8 |
VANGUARD GROUP INC |
74,250 |
566,000 |
1.99% |
|
|
| 9 |
BlackRock Investment Management, LLC |
45,793 |
349,000 |
1.23% |
|
|
| 10 |
MACKENZIE FINANCIAL CORP |
29,208 |
223,000 |
0.78% |
|
|
| 11 |
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
26,100 |
199,000 |
0.70% |
|
|
| 12 |
PANAGORA ASSET MANAGEMENT INC |
24,293 |
185,000 |
0.65% |
|
|
| 13 |
GEODE CAPITAL MANAGEMENT, LLC |
19,859 |
151,000 |
0.53% |
|
|
| 14 |
BlackRock Institutional Trust Company, N.A. |
13,100 |
100,000 |
0.35% |
|
|
| 15 |
BlackRock Fund Advisors |
10,726 |
82,000 |
0.29% |
|
|
| 16 |
BlackRock Finance, Inc. |
6,900 |
53,000 |
0.19% |
|
|
| 17 |
Ironwood Financial, llc |
870 |
7,000 |
0.02% |
|
|
| 18 |
SONORA INVESTMENT MANAGEMENT, LLC |
500 |
3,000 |
0.01% |
|
|
| 19 |
Tower Research Capital LLC (TRC) |
419 |
3,000 |
0.01% |
|
|
| 20 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
83 |
1,000 |
0.00% |
|
|
| 21 |
TCI Wealth Advisors, Inc. |
100 |
1,000 |
0.00% |
|
|
| 22 |
CITIGROUP INC |
194 |
1,000 |
0.00% |
|
|
