| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 1,022 | 5,000 | 0.01% | ||
| 2 | MORGAN STANLEY | 4,600 | 22,000 | 0.02% | ||
| 3 | Segantii Capital Management Ltd | 7,600 | 36,000 | 0.04% | ||
| 4 | Consonance Capital Management LP | 10,000 | 48,000 | 0.05% | ||
| 5 | BlueCrest Capital Management Ltd | 11,394 | 54,000 | 0.05% | ||
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 15,011 | 71,000 | 0.07% | ||
| 7 | BARCLAYS PLC | 15,314 | 73,000 | 0.07% | ||
| 8 | Spark Investment Management LLC | 19,200 | 91,000 | 0.09% | ||
| 9 | MILLENNIUM MANAGEMENT LLC | 21,952 | 104,000 | 0.10% | ||
| 10 | BlackRock Finance, Inc. | 34,727 | 165,000 | 0.17% | ||
| 11 | Granite Point Capital Management, L.P. | 595,029 | 2,826,000 | 2.84% | ||
| 12 | TREDJE AP-FONDEN | 909,581 | 4,321,000 | 4.35% | ||
| 13 | BOXER CAPITAL, LLC | 940,000 | 4,465,000 | 4.49% | ||
| 14 | Opaleye Management Inc. | 1,180,000 | 5,605,000 | 5.64% | ||
| 15 | ARMISTICE CAPITAL, LLC | 1,640,000 | 7,790,000 | 7.84% | ||
| 16 | Broadfin Capital, LLC | 2,981,706 | 14,163,000 | 14.25% | ||
| 17 | VIVO CAPITAL, LLC | 3,000,000 | 14,250,000 | 14.34% | ||
| 18 | NEA Management Company, LLC | 4,141,308 | 19,671,000 | 19.79% | ||
| 19 | CAXTON CORP | 5,394,994 | 25,626,000 | 25.78% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
