| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | CAXTON CORP | 5,394,994 | 12,948,000 | 25.10% | ||
| 2 | NEA Management Company, LLC | 4,141,308 | 9,939,000 | 19.26% | ||
| 3 | VIVO CAPITAL, LLC | 3,000,000 | 7,200,000 | 13.95% | ||
| 4 | Broadfin Capital, LLC | 2,894,581 | 6,947,000 | 13.46% | ||
| 5 | RA CAPITAL MANAGEMENT, L.P. | 2,279,099 | 5,470,000 | 10.60% | ||
| 6 | Opaleye Management Inc. | 1,160,000 | 2,784,000 | 5.40% | ||
| 7 | BOXER CAPITAL, LLC | 940,000 | 2,256,000 | 4.37% | ||
| 8 | TREDJE AP-FONDEN | 909,581 | 2,183,000 | 4.23% | ||
| 9 | Granite Point Capital Management, L.P. | 606,607 | 1,456,000 | 2.82% | ||
| 10 | Anson Funds Management LP | 92,219 | 221,000 | 0.43% | ||
| 11 | BLACKROCK ADVISORS LLC | 30,582 | 73,000 | 0.14% | ||
| 12 | BlackRock Fund Advisors | 26,448 | 63,000 | 0.12% | ||
| 13 | Spark Investment Management LLC | 16,800 | 40,000 | 0.08% | ||
| 14 | BlackRock Investment Management, LLC | 1,959 | 5,000 | 0.01% | ||
| 15 | BlackRock Japan Co. Ltd | 1,604 | 4,000 | 0.01% | ||
| 16 | DEUTSCHE BANK AG\ | 1,600 | 3,000 | 0.01% | ||
| 17 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 1,022 | 2,000 | 0.00% | ||
| 18 | ACADIAN ASSET MANAGEMENT LLC | 360 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.