| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | DEERFIELD MANAGEMENT COMPANY, L.P. | 45,000,000 | 35,876,000 | 33.81% | PRN | |
| 2 | EcoR1 Capital, LLC | 22,534,000 | 18,140,000 | 17.09% | PRN | |
| 3 | WOLVERINE ASSET MANAGEMENT LLC | 10,430,000 | 8,297,000 | 7.82% | PRN | |
| 4 | CITADEL ADVISORS LLC | 10,302,000 | 8,233,000 | 7.76% | PRN | |
| 5 | ADVENT CAPITAL MANAGEMENT /DE/ | 8,442,000 | 6,727,000 | 6.34% | PRN | |
| 6 | BARCLAYS PLC | 6,485,000 | 5,188,000 | 4.89% | PRN | |
| 7 | MACKAY SHIELDS LLC | 4,871,000 | 3,946,000 | 3.72% | PRN | |
| 8 | QVT Financial LP | 4,600,000 | 3,685,000 | 3.47% | PRN | |
| 9 | Redmile Group, LLC | 4,000,000 | 3,220,000 | 3.03% | PRN | |
| 10 | Telemetry Investments, L.L.C. | 3,000,000 | 2,415,000 | 2.28% | PRN | |
| 11 | BAKER BROS. ADVISORS LP | 3,000,000 | 2,382,000 | 2.24% | PRN | |
| 12 | BVF INC/IL | 2,500,000 | 2,025,000 | 1.91% | PRN | |
| 13 | CSS LLC/IL | 2,205,000 | 1,763,000 | 1.66% | PRN | |
| 14 | SG Americas Securities, LLC | 20,870 | 1,680,000 | 1.58% | PRN | |
| 15 | Mohican Financial Management, LLC | 1,870,000 | 1,505,000 | 1.42% | ||
| 16 | GABELLI FUNDS LLC | 1,051,000 | 846,000 | 0.80% | PRN | |
| 17 | WELLS FARGO & COMPANY/MN | 99,000 | 82,000 | 0.08% | PRN | |
| 18 | Fernwood Investment Management, LLC | 90,000 | 72,000 | 0.07% | ||
| 19 | DEUTSCHE BANK AG\ | 55,000 | 44,000 | 0.04% | PRN |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.