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MEDICINES CO
MEDICINES CO. Institutional holdings reported to the SEC.

Institutional Holders (2015Q3)
Portfolio Summary: 199 Institutional holders with a total value of $3,268,733,636.
#
Manager Name
Shares
Value ($)
%
Options
Notes
1 WELLINGTON MANAGEMENT GROUP LLP 9,334,149 354,324,000 10.84%
2 FMR LLC 9,036,792 343,036,000 10.49%
3 BlackRock Fund Advisors 5,218,933 198,111,000 6.06%
4 VANGUARD GROUP INC 4,918,209 186,695,000 5.71%
5 Corvex Management LP 3,086,803 117,175,000 3.58%
6 Invesco Ltd. 2,974,852 112,925,000 3.45%
7 Camber Capital Management LP 2,500,000 94,900,000 2.90%
8 BRIDGER MANAGEMENT, LLC 2,466,205 93,617,000 2.86%
9 Antipodean Advisors LLC 2,438,000 92,546,000 2.83%
10 MILLENNIUM MANAGEMENT LLC 2,359,573 89,569,000 2.74%
11 PointState Capital LP 2,038,541 77,383,000 2.37%
12 FRANKLIN RESOURCES INC 1,967,354 74,681,000 2.28%
13 STATE STREET CORP 1,874,234 71,144,000 2.18%
14 DIMENSIONAL FUND ADVISORS LP 1,790,128 67,951,000 2.08%
15 BlackRock Institutional Trust Company, N.A. 1,616,180 61,350,000 1.88%
16 Sarissa Capital Management LP 1,567,000 59,483,000 1.82%
17 PRICE T ROWE ASSOCIATES INC /MD/ 1,459,070 55,386,000 1.69%
18 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 1,458,788 55,376,000 1.69%
19 KORNITZER CAPITAL MANAGEMENT INC /KS 1,446,015 54,891,000 1.68%
20 PFM Health Sciences, LP 1,289,652 48,955,000 1.50%
21 EAGLE ASSET MANAGEMENT INC 1,197,846 45,470,000 1.39%
22 ALPS ADVISORS INC 104,509 39,672,000 1.21%
23 GOLDMAN SACHS GROUP INC 998,000 37,884,000 1.16% Call
24 CAMBIAR INVESTORS LLC 945,262 35,882,000 1.10%
25 JENNISON ASSOCIATES LLC 899,315 34,138,000 1.04%
26 Bank of New York Mellon Corp 791,221 30,034,000 0.92%
27 NORTHERN TRUST CORP 738,350 28,029,000 0.86%
28 PINNACLE ASSOCIATES LTD 719,399 27,308,000 0.84%
29 FRONTIER CAPITAL MANAGEMENT CO LLC 716,712 27,206,000 0.83%
30 CITADEL ADVISORS LLC 715,758 27,170,000 0.83%
31 RS INVESTMENT MANAGEMENT CO LLC 680,692 25,839,000 0.79%
32 JPMORGAN CHASE & CO 651,224 24,721,000 0.76%
33 Tekla Capital Management LLC 624,300 23,698,000 0.72%
34 Rock Springs Capital Management LP 595,000 22,586,000 0.69%
35 DEUTSCHE BANK AG\ 524,381 19,903,000 0.61%
36 GEODE CAPITAL MANAGEMENT, LLC 441,958 16,776,000 0.51%
37 PRINCIPAL FINANCIAL GROUP INC 432,096 16,403,000 0.50%
38 Retirement Systems of Alabama 425,000 16,133,000 0.49%
39 TEACHERS ADVISORS, LLC 413,507 15,697,000 0.48%
40 BNP Paribas Asset Management Holding S.A. 410,603 15,586,000 0.48%
41 ASHFORD CAPITAL MANAGEMENT INC 393,144 14,924,000 0.46%
42 PANAGORA ASSET MANAGEMENT INC 360,704 13,692,000 0.42%
43 MORGAN STANLEY 359,895 13,662,000 0.42%
44 AMERIPRISE FINANCIAL INC 359,623 13,652,000 0.42%
45 NORGES BANK 344,184 13,065,000 0.40%
46 GOLDMAN SACHS GROUP INC 338,856 12,863,000 0.39%
47 MACQUARIE GROUP LTD 331,874 12,598,000 0.39%
48 TIAA CREF INVESTMENT MANAGEMENT LLC 320,221 12,156,000 0.37%
49 Elk Creek Partners, LLC 311,816 11,837,000 0.36%
50 UNITED SERVICES AUTOMOBILE ASSOCIATION 310,325 11,780,000 0.36%
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From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.