| 1 |
MPM ASSET MANAGEMENT LLC |
1,192,080 |
9,704,000 |
18.65% |
|
|
| 2 |
Polar Capital LLP |
900,604 |
7,326,000 |
14.08% |
|
|
| 3 |
JENNISON ASSOCIATES LLC |
849,881 |
6,914,000 |
13.29% |
|
|
| 4 |
ADAGE CAPITAL PARTNERS GP, L.L.C. |
550,000 |
4,474,000 |
8.60% |
|
|
| 5 |
JANUS HENDERSON INVESTORS US LLC |
515,605 |
4,194,000 |
8.06% |
|
|
| 6 |
AXA S.A. |
292,625 |
2,381,000 |
4.58% |
|
|
| 7 |
Ghost Tree Capital, LLC |
219,977 |
1,790,000 |
3.44% |
|
|
| 8 |
PUTNAM INVESTMENTS LLC |
217,264 |
1,767,000 |
3.40% |
|
|
| 9 |
BlackRock Fund Advisors |
164,931 |
1,342,000 |
2.58% |
|
|
| 10 |
BLACKROCK ADVISORS LLC |
157,622 |
1,283,000 |
2.47% |
|
|
| 11 |
JBF Capital, Inc. |
148,178 |
1,205,000 |
2.32% |
|
|
| 12 |
VANGUARD GROUP INC |
134,564 |
1,095,000 |
2.10% |
|
|
| 13 |
MILLENNIUM MANAGEMENT LLC |
100,000 |
814,000 |
1.56% |
|
|
| 14 |
Weiss Multi-Strategy Advisers LLC |
95,000 |
773,000 |
1.49% |
|
|
| 15 |
NORTHERN TRUST CORP |
86,375 |
703,000 |
1.35% |
|
|
| 16 |
MORGAN STANLEY |
84,488 |
688,000 |
1.32% |
|
|
| 17 |
SPHERA FUNDS MANAGEMENT LTD. |
80,000 |
651,000 |
1.25% |
|
|
| 18 |
Bank of New York Mellon Corp |
71,676 |
583,000 |
1.12% |
|
|
| 19 |
Jasper Ridge Partners, L.P. |
63,996 |
521,000 |
1.00% |
|
|
| 20 |
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS |
58,700 |
478,000 |
0.92% |
|
|
| 21 |
BlackRock Institutional Trust Company, N.A. |
55,204 |
449,000 |
0.86% |
|
|
| 22 |
BlackRock Group LTD |
47,700 |
388,000 |
0.75% |
|
|
| 23 |
STATE STREET CORP |
45,906 |
373,000 |
0.72% |
|
|
| 24 |
GEODE CAPITAL MANAGEMENT, LLC |
34,969 |
284,000 |
0.55% |
|
|
| 25 |
HAMILTON LANE ADVISORS LLC |
33,141 |
270,000 |
0.52% |
|
|
| 26 |
DRIEHAUS CAPITAL MANAGEMENT LLC |
22,800 |
185,000 |
0.36% |
|
|
| 27 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
20,000 |
163,000 |
0.31% |
|
|
| 28 |
GOLDMAN SACHS GROUP INC |
19,976 |
163,000 |
0.31% |
|
|
| 29 |
BlackRock Investment Management, LLC |
17,700 |
144,000 |
0.28% |
|
|
| 30 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
16,227 |
132,000 |
0.25% |
|
|
| 31 |
BANQUE PICTET & CIE SA |
15,849 |
129,000 |
0.25% |
|
|
| 32 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
12,700 |
104,000 |
0.20% |
|
|
| 33 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
10,800 |
88,000 |
0.17% |
|
|
| 34 |
Virtu KCG Holdings LLC |
10,561 |
86,000 |
0.17% |
|
|
| 35 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
10,000 |
74,000 |
0.14% |
|
|
| 36 |
BANK OF MONTREAL /CAN/ |
7,000 |
57,000 |
0.11% |
|
|
| 37 |
SHAPIRO ROBERT N |
5,973 |
49,000 |
0.09% |
|
|
| 38 |
TEACHERS ADVISORS, LLC |
5,590 |
45,000 |
0.09% |
|
|
| 39 |
Tower Research Capital LLC (TRC) |
5,099 |
42,000 |
0.08% |
|
|
| 40 |
Nationwide Fund Advisors |
4,742 |
39,000 |
0.07% |
|
|
| 41 |
AMERICAN INTERNATIONAL GROUP, INC. |
4,079 |
33,183 |
0.06% |
|
|
| 42 |
DEUTSCHE BANK AG\ |
2,606 |
20,000 |
0.04% |
|
|
| 43 |
CITIGROUP INC |
927 |
8,000 |
0.02% |
|
|
| 44 |
Creative Planning |
1,000 |
8,000 |
0.02% |
|
|
| 45 |
MAGEE THOMSON INVESTMENT PARTNERS LLC |
413 |
4,000 |
0.01% |
|
|
| 46 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
200 |
2,000 |
0.00% |
|
|
| 47 |
BARCLAYS PLC |
237 |
2,000 |
0.00% |
|
|
| 48 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
176 |
1,000 |
0.00% |
|
|
| 49 |
STRS OHIO |
0 |
0 |
0.00% |
|
|
| 50 |
WELLS FARGO & COMPANY/MN |
1 |
0 |
0.00% |
|
|
