| 1 |
MPM ASSET MANAGEMENT LLC |
1,192,080 |
5,305,000 |
16.82% |
|
|
| 2 |
AXA S.A. |
1,093,345 |
4,865,000 |
15.42% |
|
|
| 3 |
HealthCor Management, L.P. |
1,008,500 |
4,488,000 |
14.23% |
|
|
| 4 |
JENNISON ASSOCIATES LLC |
659,067 |
2,933,000 |
9.30% |
|
|
| 5 |
MILLENNIUM MANAGEMENT LLC |
556,680 |
2,477,000 |
7.85% |
|
|
| 6 |
VANGUARD GROUP INC |
389,533 |
1,733,000 |
5.49% |
|
|
| 7 |
CITADEL ADVISORS LLC |
379,695 |
1,690,000 |
5.36% |
|
|
| 8 |
Iguana Healthcare Management, LLC |
300,000 |
1,335,000 |
4.23% |
|
|
| 9 |
PUTNAM INVESTMENTS LLC |
190,527 |
848,000 |
2.69% |
|
|
| 10 |
CITIGROUP INC |
158,036 |
703,000 |
2.23% |
|
|
| 11 |
Polar Capital LLP |
156,531 |
695,000 |
2.20% |
|
|
| 12 |
UNITED CAPITAL FINANCIAL ADVISORS, LLC |
124,943 |
556,000 |
1.76% |
|
|
| 13 |
Nine Chapters Capital Management LLC |
97,700 |
435,000 |
1.38% |
|
|
| 14 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
95,800 |
426,000 |
1.35% |
Put |
|
| 15 |
GEODE CAPITAL MANAGEMENT, LLC |
76,380 |
339,000 |
1.07% |
|
|
| 16 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
74,500 |
332,000 |
1.05% |
|
|
| 17 |
Bank of New York Mellon Corp |
63,604 |
283,000 |
0.90% |
|
|
| 18 |
SABBY MANAGEMENT, LLC |
62,500 |
278,000 |
0.88% |
|
|
| 19 |
A.R.T. Advisors, LLC |
51,811 |
230,000 |
0.73% |
|
|
| 20 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
38,480 |
171,000 |
0.54% |
|
|
| 21 |
ELLINGTON MANAGEMENT GROUP LLC |
36,300 |
162,000 |
0.51% |
|
|
| 22 |
CITIGROUP INC |
34,000 |
151,000 |
0.48% |
Call |
|
| 23 |
BlackRock Fund Advisors |
33,443 |
149,000 |
0.47% |
|
|
| 24 |
REILLY FINANCIAL ADVISORS, LLC |
32,011 |
142,000 |
0.45% |
|
|
| 25 |
DEUTSCHE BANK AG\ |
30,938 |
137,000 |
0.43% |
|
|
| 26 |
MORGAN STANLEY |
27,223 |
121,000 |
0.38% |
|
|
| 27 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
24,900 |
111,000 |
0.35% |
|
|
| 28 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
24,500 |
109,000 |
0.35% |
Call |
|
| 29 |
NORTHERN TRUST CORP |
22,259 |
99,000 |
0.31% |
|
|
| 30 |
Jasper Ridge Partners, L.P. |
21,332 |
95,000 |
0.30% |
|
|
| 31 |
BlackRock Institutional Trust Company, N.A. |
19,182 |
85,000 |
0.27% |
|
|
| 32 |
GROUP ONE TRADING LLC |
5,542 |
25,000 |
0.08% |
|
|
| 33 |
BlackRock Investment Management, LLC |
2,287 |
10,000 |
0.03% |
|
|
| 34 |
Tower Research Capital LLC (TRC) |
2,242 |
10,000 |
0.03% |
|
|
| 35 |
Walleye Trading LLC |
1,100 |
5,000 |
0.02% |
|
|
| 36 |
PNC FINANCIAL SERVICES GROUP, INC. |
1,000 |
4,000 |
0.01% |
|
|
| 37 |
Creative Planning |
1,000 |
4,000 |
0.01% |
|
|
| 38 |
WELLS FARGO & COMPANY/MN |
600 |
3,000 |
0.01% |
|
|
| 39 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
500 |
2,000 |
0.01% |
|
|
| 40 |
PERCEPTIVE ADVISORS LLC |
425 |
2,000 |
0.01% |
|
|
| 41 |
BARCLAYS PLC |
14 |
0 |
0.00% |
|
|
