| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Aisling Capital LLC | 2,030,175 | 34,570,000 | 14.69% | ||
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 1,942,397 | 33,079,000 | 14.06% | ||
| 3 | Canaan Partners VII LLC | 1,902,030 | 32,392,000 | 13.77% | ||
| 4 | ORBIMED ADVISORS LLC | 1,785,714 | 30,411,000 | 12.92% | ||
| 5 | OppenheimerFunds, Inc. | 1,000,000 | 17,030,000 | 7.24% | ||
| 6 | FMR LLC | 731,951 | 12,465,000 | 5.30% | ||
| 7 | Granahan Investment Management, LLC | 692,639 | 11,796,000 | 5.01% | ||
| 8 | BlackRock Fund Advisors | 380,704 | 6,483,000 | 2.76% | ||
| 9 | VANGUARD GROUP INC | 320,867 | 5,465,000 | 2.32% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 191,986 | 3,270,000 | 1.39% | ||
| 11 | Informed Momentum Co LLC | 187,925 | 3,200,000 | 1.36% | ||
| 12 | STATE STREET CORP | 177,894 | 3,031,000 | 1.29% | ||
| 13 | Allianz Asset Management GmbH | 166,691 | 2,839,000 | 1.21% | ||
| 14 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 152,500 | 2,597,000 | 1.10% | Put | |
| 15 | NORTHERN TRUST CORP | 148,211 | 2,524,000 | 1.07% | ||
| 16 | MASON STREET ADVISORS, LLC | 138,790 | 2,364,000 | 1.00% | ||
| 17 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 133,300 | 2,270,000 | 0.96% | ||
| 18 | MORGAN STANLEY | 92,891 | 1,582,000 | 0.67% | ||
| 19 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 76,150 | 1,297,000 | 0.55% | ||
| 20 | UBS AG | 75,400 | 1,284,000 | 0.55% | Put | |
| 21 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 72,326 | 1,232,000 | 0.52% | ||
| 22 | Bank of New York Mellon Corp | 67,458 | 1,149,000 | 0.49% | ||
| 23 | RENAISSANCE TECHNOLOGIES LLC | 66,200 | 1,127,000 | 0.48% | ||
| 24 | JANE STREET GROUP, LLC | 66,053 | 1,125,000 | 0.48% | ||
| 25 | BANK OF AMERICA CORP /DE/ | 61,171 | 1,041,000 | 0.44% | ||
| 26 | GEODE CAPITAL MANAGEMENT, LLC | 59,242 | 1,008,000 | 0.43% | ||
| 27 | ROYAL BANK OF CANADA | 58,500 | 996,000 | 0.42% | ||
| 28 | TIAA CREF INVESTMENT MANAGEMENT LLC | 58,008 | 988,000 | 0.42% | ||
| 29 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 55,000 | 937,000 | 0.40% | ||
| 30 | AMERICAN INTERNATIONAL GROUP, INC. | 54,696 | 931,473 | 0.40% | ||
| 31 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 53,000 | 903,000 | 0.38% | Call | |
| 32 | PDT Partners, LLC | 51,556 | 878,000 | 0.37% | ||
| 33 | GOLDMAN SACHS GROUP INC | 50,400 | 858,000 | 0.36% | Call | |
| 34 | BlackRock Investment Management, LLC | 44,926 | 765,000 | 0.33% | ||
| 35 | RUSSELL FRANK CO/ | 55,155 | 721,000 | 0.31% | ||
| 36 | Nationwide Fund Advisors | 41,961 | 715,000 | 0.30% | ||
| 37 | Spark Investment Management LLC | 39,442 | 671,000 | 0.29% | ||
| 38 | GROUP ONE TRADING LLC | 38,045 | 648,000 | 0.28% | ||
| 39 | MILLENNIUM MANAGEMENT LLC | 37,918 | 646,000 | 0.27% | ||
| 40 | AQR CAPITAL MANAGEMENT LLC | 33,600 | 572,000 | 0.24% | ||
| 41 | ANALYTIC INVESTORS, LLC | 32,563 | 555,000 | 0.24% | ||
| 42 | GABELLI FUNDS LLC | 32,000 | 545,000 | 0.23% | ||
| 43 | UBS AG | 30,166 | 513,000 | 0.22% | ||
| 44 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 28,388 | 483,000 | 0.21% | ||
| 45 | HAMILTON LANE ADVISORS LLC | 26,228 | 447,000 | 0.19% | ||
| 46 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 25,300 | 431,000 | 0.18% | ||
| 47 | CITIGROUP INC | 25,000 | 426,000 | 0.18% | Call | |
| 48 | TEACHERS ADVISORS, LLC | 21,512 | 366,000 | 0.16% | ||
| 49 | STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 21,233 | 362,000 | 0.15% | ||
| 50 | PANAGORA ASSET MANAGEMENT INC | 19,811 | 337,000 | 0.14% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
