| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Third Security, LLC | 16,620,414 | 63,989,000 | 52.33% | ||
| 2 | FMR LLC | 3,606,440 | 13,885,000 | 11.36% | ||
| 3 | JENNISON ASSOCIATES LLC | 2,807,961 | 10,811,000 | 8.84% | ||
| 4 | MSD Partners, L.P. | 1,997,644 | 7,691,000 | 6.29% | ||
| 5 | QVT Financial LP | 1,870,556 | 7,202,000 | 5.89% | ||
| 6 | VANGUARD GROUP INC | 818,546 | 3,151,000 | 2.58% | ||
| 7 | BlackRock Fund Advisors | 676,396 | 2,604,000 | 2.13% | ||
| 8 | EMERALD ADVISERS, LLC | 324,425 | 1,249,000 | 1.02% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 292,050 | 1,124,000 | 0.92% | ||
| 10 | Invesco Ltd. | 275,519 | 1,061,000 | 0.87% | ||
| 11 | NORTHERN TRUST CORP | 269,120 | 1,036,000 | 0.85% | ||
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 206,043 | 793,000 | 0.65% | ||
| 13 | STATE STREET CORP | 197,695 | 760,000 | 0.62% | ||
| 14 | Cambridge Investment Research Advisors, Inc. | 195,851 | 754,000 | 0.62% | ||
| 15 | Bank of New York Mellon Corp | 156,192 | 601,000 | 0.49% | ||
| 16 | Healthcare Value Capital, LLC | 147,769 | 569,000 | 0.47% | ||
| 17 | Trellus Management Company, LLC | 114,936 | 443,000 | 0.36% | ||
| 18 | STALEY CAPITAL ADVISERS INC | 110,000 | 423,000 | 0.35% | ||
| 19 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 109,000 | 420,000 | 0.34% | ||
| 20 | BlackRock Investment Management, LLC | 92,307 | 355,000 | 0.29% | ||
| 21 | Catalyst Capital Advisors LLC | 89,472 | 344,000 | 0.28% | ||
| 22 | STONERIDGE INVESTMENT PARTNERS LLC | 86,004 | 331,000 | 0.27% | ||
| 23 | TIAA CREF INVESTMENT MANAGEMENT LLC | 82,089 | 316,000 | 0.26% | ||
| 24 | CITIGROUP INC | 55,173 | 212,000 | 0.17% | ||
| 25 | AKANTHOS CAPITAL MANAGEMENT LLC | 50,000 | 192,000 | 0.16% | ||
| 26 | NEW YORK STATE COMMON RETIREMENT FUND | 48,912 | 188,000 | 0.15% | ||
| 27 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 47,557 | 183,000 | 0.15% | ||
| 28 | MORGAN STANLEY | 42,431 | 163,000 | 0.13% | ||
| 29 | Spark Investment Management LLC | 41,500 | 159,000 | 0.13% | ||
| 30 | TEACHERS ADVISORS, LLC | 36,143 | 139,000 | 0.11% | ||
| 31 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 34,944 | 135,000 | 0.11% | ||
| 32 | GOLDMAN SACHS GROUP INC | 35,060 | 135,000 | 0.11% | ||
| 33 | Context Capital Management, LLC | 31,010 | 119,000 | 0.10% | ||
| 34 | BRANDES INVESTMENT PARTNERS, LP | 22,600 | 87,000 | 0.07% | ||
| 35 | Virtu KCG Holdings LLC | 22,337 | 86,000 | 0.07% | ||
| 36 | RHUMBLINE ADVISERS | 21,269 | 82,000 | 0.07% | ||
| 37 | Geduld E E | 20,100 | 77,000 | 0.06% | ||
| 38 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 17,348 | 67,000 | 0.05% | ||
| 39 | Nationwide Fund Advisors | 17,401 | 67,000 | 0.05% | ||
| 40 | BLACKROCK ADVISORS LLC | 16,716 | 64,000 | 0.05% | ||
| 41 | AMERICAN INTERNATIONAL GROUP, INC. | 14,410 | 55,000 | 0.04% | ||
| 42 | STRS OHIO | 13,400 | 51,000 | 0.04% | ||
| 43 | Creative Planning | 9,000 | 35,000 | 0.03% | ||
| 44 | DEUTSCHE BANK AG\ | 7,198 | 27,000 | 0.02% | ||
| 45 | BNP PARIBAS FINANCIAL MARKETS | 5,403 | 20,802 | 0.02% | ||
| 46 | WELLS FARGO & COMPANY/MN | 1,171 | 5,000 | 0.00% | ||
| 47 | ROYAL BANK OF CANADA | 1,062 | 4,000 | 0.00% | ||
| 48 | SIGNATUREFD, LLC | 1,000 | 4,000 | 0.00% | ||
| 49 | TCI Wealth Advisors, Inc. | 700 | 3,000 | 0.00% | ||
| 50 | UBS Group AG | 494 | 2,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
