| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PRIMECAP MANAGEMENT CO/CA/ | 3,651,332 | 107,349,000 | 13.10% | ||
| 2 | JENNISON ASSOCIATES LLC | 3,085,932 | 90,726,000 | 11.07% | ||
| 3 | JPMORGAN CHASE & CO | 2,506,719 | 73,698,000 | 8.99% | ||
| 4 | ORBIMED ADVISORS LLC | 1,862,200 | 54,749,000 | 6.68% | ||
| 5 | WASATCH ADVISORS LP | 1,741,471 | 51,199,000 | 6.25% | ||
| 6 | FRANKLIN RESOURCES INC | 1,348,935 | 39,659,000 | 4.84% | ||
| 7 | NEXT CENTURY GROWTH INVESTORS LLC | 1,253,599 | 36,855,000 | 4.50% | ||
| 8 | FMR LLC | 1,126,545 | 33,120,000 | 4.04% | ||
| 9 | VANGUARD GROUP INC | 847,863 | 24,928,000 | 3.04% | ||
| 10 | BlackRock Fund Advisors | 786,991 | 23,138,000 | 2.82% | ||
| 11 | LORD, ABBETT & CO. LLC | 660,346 | 19,414,000 | 2.37% | ||
| 12 | ZEVENBERGEN CAPITAL INVESTMENTS LLC | 573,000 | 16,846,000 | 2.06% | ||
| 13 | RS INVESTMENT MANAGEMENT CO LLC | 524,648 | 15,425,000 | 1.88% | ||
| 14 | GOLDMAN SACHS GROUP INC | 484,400 | 14,241,000 | 1.74% | Call | |
| 15 | STATE STREET CORP | 416,750 | 12,256,000 | 1.50% | ||
| 16 | Redmile Group, LLC | 392,540 | 11,541,000 | 1.41% | ||
| 17 | BlackRock Institutional Trust Company, N.A. | 344,927 | 10,141,000 | 1.24% | ||
| 18 | SANDLER CAPITAL MANAGEMENT | 323,700 | 9,517,000 | 1.16% | ||
| 19 | NORTHERN TRUST CORP | 320,139 | 9,411,000 | 1.15% | ||
| 20 | Invesco Ltd. | 316,359 | 9,301,000 | 1.14% | ||
| 21 | CI Global Investments Inc. | 300,000 | 8,820,000 | 1.08% | ||
| 22 | SCHRODER INVESTMENT MANAGEMENT GROUP | 289,700 | 8,517,180 | 1.04% | ||
| 23 | MILLENNIUM MANAGEMENT LLC | 265,391 | 7,802,000 | 0.95% | ||
| 24 | Pier Capital, LLC | 254,135 | 7,472,000 | 0.91% | ||
| 25 | ORBIMED ADVISORS LLC | 250,000 | 7,350,000 | 0.90% | Call | |
| 26 | GOLDMAN SACHS GROUP INC | 240,000 | 7,056,000 | 0.86% | Put | |
| 27 | Stephens Investment Management Group LLC | 229,375 | 6,744,000 | 0.82% | ||
| 28 | RUSSELL FRANK CO/ | 201,055 | 5,911,000 | 0.72% | ||
| 29 | GEODE CAPITAL MANAGEMENT, LLC | 152,333 | 4,478,000 | 0.55% | ||
| 30 | OppenheimerFunds, Inc. | 148,384 | 4,362,000 | 0.53% | ||
| 31 | Bank of New York Mellon Corp | 144,011 | 4,234,000 | 0.52% | ||
| 32 | Allianz Asset Management GmbH | 118,292 | 3,478,000 | 0.42% | ||
| 33 | CREDIT SUISSE AG/ | 113,755 | 3,345,000 | 0.41% | ||
| 34 | TIAA CREF INVESTMENT MANAGEMENT LLC | 112,112 | 3,296,000 | 0.40% | ||
| 35 | IRONBRIDGE CAPITAL MANAGEMENT LP | 110,923 | 3,261,000 | 0.40% | ||
| 36 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 104,002 | 3,057,000 | 0.37% | ||
| 37 | Cupps Capital Management, LLC | 103,261 | 3,035,000 | 0.37% | ||
| 38 | Visium Asset Management, LP | 95,200 | 2,799,000 | 0.34% | ||
| 39 | Elk Creek Partners, LLC | 94,547 | 2,780,000 | 0.34% | ||
| 40 | D. E. Shaw & Co., Inc. | 84,872 | 2,495,000 | 0.30% | ||
| 41 | STIFEL FINANCIAL CORP | 83,035 | 2,441,000 | 0.30% | ||
| 42 | BlackRock Investment Management, LLC | 80,993 | 2,381,000 | 0.29% | ||
| 43 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 72,531 | 2,133,000 | 0.26% | ||
| 44 | First Light Asset Management, LLC | 72,451 | 2,130,000 | 0.26% | ||
| 45 | PRINCIPAL FINANCIAL GROUP INC | 70,693 | 2,078,000 | 0.25% | ||
| 46 | WALL STREET ASSOCIATES | 69,065 | 2,031,000 | 0.25% | ||
| 47 | DRIEHAUS CAPITAL MANAGEMENT LLC | 64,151 | 1,886,000 | 0.23% | ||
| 48 | 1832 Asset Management L.P. | 63,482 | 1,868,000 | 0.23% | ||
| 49 | Numeric Investors LLC | 61,000 | 1,793,000 | 0.22% | ||
| 50 | VIRTUS CAPITAL ADVISERS, LLC | 55,486 | 1,631,000 | 0.20% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
