| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Invesco Ltd. | 6,317,851 | 22,555,000 | 47.64% | ||
| 2 | Abingworth LLP | 3,473,452 | 12,331,000 | 26.04% | ||
| 3 | SV Health Investors, LLC | 1,077,499 | 3,847,000 | 8.13% | ||
| 4 | Aisling Capital LLC | 886,363 | 3,164,000 | 6.68% | ||
| 5 | FIL Ltd | 786,997 | 2,865,000 | 6.05% | ||
| 6 | Alyeska Investment Group, L.P. | 167,004 | 596,000 | 1.26% | ||
| 7 | CITADEL ADVISORS LLC | 160,605 | 585,000 | 1.24% | ||
| 8 | DEUTSCHE BANK AG\ | 102,005 | 364,000 | 0.77% | ||
| 9 | Weiss Multi-Strategy Advisers LLC | 97,000 | 346,000 | 0.73% | ||
| 10 | PURA VIDA INVESTMENTS, LLC | 52,875 | 189,000 | 0.40% | ||
| 11 | BlackRock Fund Advisors | 33,163 | 118,000 | 0.25% | ||
| 12 | Spark Investment Management LLC | 26,400 | 93,000 | 0.20% | ||
| 13 | Verition Fund Management LLC | 19,129 | 70,000 | 0.15% | ||
| 14 | AMERICAN INTERNATIONAL GROUP, INC. | 18,985 | 68,000 | 0.14% | ||
| 15 | HSBC HOLDINGS PLC | 18,236 | 66,000 | 0.14% | ||
| 16 | GOLDMAN SACHS GROUP INC | 15,800 | 56,000 | 0.12% | ||
| 17 | UBS Group AG | 4,001 | 14,000 | 0.03% | ||
| 18 | BlackRock Investment Management, LLC | 2,008 | 7,000 | 0.01% | ||
| 19 | MORGAN STANLEY | 1,945 | 7,000 | 0.01% | ||
| 20 | Tower Research Capital LLC (TRC) | 1,345 | 5,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
