| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ROYAL BANK OF CANADA | 135 | 0 | 0.00% | ||
| 2 | MORGAN STANLEY | 1,863 | 1,000 | 0.01% | ||
| 3 | HSBC HOLDINGS PLC | 18,236 | 11,000 | 0.15% | ||
| 4 | GOLDMAN SACHS GROUP INC | 22,550 | 14,000 | 0.19% | ||
| 5 | UBS Group AG | 24,563 | 15,000 | 0.21% | ||
| 6 | New Leaf Venture Partners, L.L.C. | 1,072,634 | 643,000 | 8.84% | ||
| 7 | SV Health Investors, LLC | 1,275,779 | 765,000 | 10.52% | ||
| 8 | Abingworth LLP | 3,473,452 | 2,032,000 | 27.95% | ||
| 9 | Invesco Ltd. | 6,317,851 | 3,790,000 | 52.12% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
