| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ROYAL BANK OF CANADA | 135 | 0 | 0.00% | ||
| 2 | MORGAN STANLEY | 1,865 | 1,000 | 0.01% | ||
| 3 | UBS Group AG | 7,904 | 6,000 | 0.06% | ||
| 4 | DEUTSCHE BANK AG\ | 18,526 | 14,000 | 0.15% | ||
| 5 | Verition Fund Management LLC | 19,129 | 15,000 | 0.16% | ||
| 6 | HSBC HOLDINGS PLC | 18,236 | 15,000 | 0.16% | ||
| 7 | GOLDMAN SACHS GROUP INC | 22,550 | 18,000 | 0.19% | ||
| 8 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 22,786 | 18,000 | 0.19% | ||
| 9 | RENAISSANCE TECHNOLOGIES LLC | 27,734 | 22,000 | 0.23% | ||
| 10 | Virtu KCG Holdings LLC | 78,148 | 61,000 | 0.63% | ||
| 11 | New Leaf Venture Partners, L.L.C. | 1,072,634 | 837,000 | 8.68% | ||
| 12 | SV Health Investors, LLC | 1,275,779 | 995,000 | 10.32% | ||
| 13 | Abingworth LLP | 3,473,452 | 2,709,000 | 28.10% | ||
| 14 | Invesco Ltd. | 6,317,851 | 4,928,000 | 51.13% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
