| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 17,409,085 | 145,714,000 | 20.45% | ||
| 2 | VANGUARD GROUP INC | 9,238,227 | 77,324,000 | 10.85% | ||
| 3 | WESTFIELD CAPITAL MANAGEMENT CO LP | 8,127,022 | 68,023,000 | 9.55% | ||
| 4 | Consonance Capital Management LP | 5,875,171 | 49,175,000 | 6.90% | ||
| 5 | TIAA CREF INVESTMENT MANAGEMENT LLC | 5,465,496 | 45,746,000 | 6.42% | ||
| 6 | BlackRock Fund Advisors | 5,283,448 | 44,222,000 | 6.21% | ||
| 7 | STATE STREET CORP | 2,968,888 | 24,850,000 | 3.49% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 2,842,035 | 23,788,000 | 3.34% | ||
| 9 | PUTNAM INVESTMENTS LLC | 2,670,971 | 22,356,000 | 3.14% | ||
| 10 | TEACHERS ADVISORS, LLC | 2,530,188 | 21,178,000 | 2.97% | ||
| 11 | Lagoda Investment Management, L.P. | 2,327,599 | 19,482,000 | 2.73% | ||
| 12 | DEUTSCHE BANK AG\ | 1,819,617 | 15,228,000 | 2.14% | ||
| 13 | NORTHERN TRUST CORP | 1,339,012 | 11,207,000 | 1.57% | ||
| 14 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,308,762 | 10,954,000 | 1.54% | ||
| 15 | Cannell & Co. | 1,176,978 | 9,851,000 | 1.38% | ||
| 16 | MORGAN STANLEY | 875,504 | 7,328,000 | 1.03% | ||
| 17 | GEODE CAPITAL MANAGEMENT, LLC | 773,750 | 6,476,000 | 0.91% | ||
| 18 | ROYAL BANK OF CANADA | 729,484 | 6,105,000 | 0.86% | ||
| 19 | Bank of New York Mellon Corp | 660,162 | 5,525,000 | 0.78% | ||
| 20 | RENAISSANCE TECHNOLOGIES LLC | 636,613 | 5,328,000 | 0.75% | ||
| 21 | Tekla Capital Management LLC | 569,894 | 4,770,000 | 0.67% | ||
| 22 | NORGES BANK | 527,326 | 4,414,000 | 0.62% | ||
| 23 | Connor, Clark & Lunn Investment Management Ltd. | 490,200 | 4,103,000 | 0.58% | ||
| 24 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 430,069 | 3,600,000 | 0.51% | ||
| 25 | VOYA INVESTMENT MANAGEMENT LLC | 422,976 | 3,541,000 | 0.50% | ||
| 26 | GUGGENHEIM CAPITAL LLC | 419,708 | 3,513,000 | 0.49% | ||
| 27 | AXA S.A. | 417,943 | 3,498,000 | 0.49% | ||
| 28 | BlackRock Investment Management, LLC | 401,507 | 3,361,000 | 0.47% | ||
| 29 | CREDIT SUISSE AG/ | 361,882 | 3,030,000 | 0.43% | ||
| 30 | PointState Capital LP | 350,000 | 2,930,000 | 0.41% | ||
| 31 | JPMORGAN CHASE & CO | 329,234 | 2,756,000 | 0.39% | ||
| 32 | BLAIR WILLIAM & CO/IL | 304,350 | 2,547,000 | 0.36% | ||
| 33 | QS Investors, LLC | 277,409 | 2,322,000 | 0.33% | ||
| 34 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 244,830 | 2,049,000 | 0.29% | ||
| 35 | Alberta Investment Management Corp | 232,430 | 1,945,000 | 0.27% | ||
| 36 | Portolan Capital Management, LLC | 227,051 | 1,900,000 | 0.27% | ||
| 37 | NEW YORK STATE COMMON RETIREMENT FUND | 219,253 | 1,835,000 | 0.26% | ||
| 38 | Candriam S.C.A. | 217,000 | 1,806,000 | 0.25% | ||
| 39 | BROWN ADVISORY INC | 210,294 | 1,760,000 | 0.25% | ||
| 40 | STONERIDGE INVESTMENT PARTNERS LLC | 180,534 | 1,511,000 | 0.21% | ||
| 41 | Swiss National Bank | 176,000 | 1,423,000 | 0.20% | ||
| 42 | ALLIANCEBERNSTEIN L.P. | 168,300 | 1,409,000 | 0.20% | ||
| 43 | CAMBRIDGE TRUST CO | 143,003 | 1,197,000 | 0.17% | ||
| 44 | UBS Group AG | 138,800 | 1,162,000 | 0.16% | ||
| 45 | J.P. Morgan Private Wealth Advisors LLC | 129,401 | 1,083,000 | 0.15% | ||
| 46 | RHUMBLINE ADVISERS | 115,250 | 965,000 | 0.14% | ||
| 47 | CITADEL ADVISORS LLC | 114,748 | 960,000 | 0.13% | ||
| 48 | BLACKROCK ADVISORS LLC | 112,703 | 944,000 | 0.13% | ||
| 49 | CITIGROUP INC | 105,007 | 879,000 | 0.12% | ||
| 50 | ProShare Advisors LLC | 100,059 | 837,000 | 0.12% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
