| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 10,773,450 | 143,826,000 | 16.44% | ||
| 2 | BlackRock Finance, Inc. | 8,774,070 | 117,134,000 | 13.39% | ||
| 3 | VANGUARD GROUP INC | 5,953,677 | 79,481,000 | 9.08% | ||
| 4 | Invesco Ltd. | 3,644,648 | 48,656,000 | 5.56% | ||
| 5 | DISCOVERY CAPITAL MANAGEMENT, LLC / CT | 3,020,102 | 40,318,000 | 4.61% | ||
| 6 | PRIMECAP MANAGEMENT CO/CA/ | 2,739,900 | 36,578,000 | 4.18% | ||
| 7 | STATE STREET CORP | 2,455,449 | 32,776,000 | 3.75% | ||
| 8 | ORBIMED ADVISORS LLC | 2,109,068 | 28,156,000 | 3.22% | ||
| 9 | Fiera Capital Corp | 1,849,216 | 24,687,000 | 2.82% | ||
| 10 | Palo Alto Investors LP | 1,759,376 | 23,488,000 | 2.68% | ||
| 11 | D. E. Shaw & Co., Inc. | 1,651,026 | 22,041,000 | 2.52% | ||
| 12 | NORGES BANK | 1,575,964 | 21,039,000 | 2.40% | ||
| 13 | Numeric Investors LLC | 937,485 | 12,515,000 | 1.43% | ||
| 14 | PRICE T ROWE ASSOCIATES INC /MD/ | 884,568 | 11,809,000 | 1.35% | ||
| 15 | NORTHERN TRUST CORP | 806,345 | 10,765,000 | 1.23% | ||
| 16 | Bank of New York Mellon Corp | 793,735 | 10,596,000 | 1.21% | ||
| 17 | BANK OF AMERICA CORP /DE/ | 780,999 | 10,426,000 | 1.19% | ||
| 18 | SECTOR GAMMA AS | 756,765 | 10,103,000 | 1.15% | ||
| 19 | DIMENSIONAL FUND ADVISORS LP | 726,515 | 9,699,000 | 1.11% | ||
| 20 | JPMORGAN CHASE & CO | 636,744 | 8,500,000 | 0.97% | ||
| 21 | GEODE CAPITAL MANAGEMENT, LLC | 528,877 | 7,059,000 | 0.81% | ||
| 22 | PRINCIPAL FINANCIAL GROUP INC | 516,542 | 6,896,000 | 0.79% | ||
| 23 | TEACHERS ADVISORS, LLC | 515,384 | 6,880,000 | 0.79% | ||
| 24 | Tekla Capital Management LLC | 504,400 | 6,734,000 | 0.77% | ||
| 25 | GOLDMAN SACHS GROUP INC | 494,399 | 6,600,000 | 0.75% | ||
| 26 | SECTORAL ASSET MANAGEMENT INC | 460,300 | 6,145,000 | 0.70% | ||
| 27 | Opaleye Management Inc. | 440,000 | 5,874,000 | 0.67% | ||
| 28 | FORESITE CAPITAL MANAGEMENT III, LLC | 430,632 | 5,749,000 | 0.66% | ||
| 29 | EDMOND DE ROTHSCHILD HOLDING S.A. | 420,000 | 5,607,000 | 0.64% | ||
| 30 | AMERIPRISE FINANCIAL INC | 341,666 | 4,562,000 | 0.52% | ||
| 31 | SENZAR ASSET MANAGEMENT, LLC | 313,296 | 4,183,000 | 0.48% | ||
| 32 | Pier Capital, LLC | 309,299 | 4,129,000 | 0.47% | ||
| 33 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 293,238 | 3,915,000 | 0.45% | ||
| 34 | RENAISSANCE TECHNOLOGIES LLC | 278,400 | 3,717,000 | 0.42% | ||
| 35 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 275,768 | 3,682,000 | 0.42% | ||
| 36 | MORGAN STANLEY | 273,724 | 3,655,000 | 0.42% | ||
| 37 | NEW YORK STATE COMMON RETIREMENT FUND | 261,738 | 3,494,000 | 0.40% | ||
| 38 | South Dakota Investment Council | 257,652 | 3,440,000 | 0.39% | ||
| 39 | Candriam S.C.A. | 210,000 | 2,804,000 | 0.32% | ||
| 40 | QS Investors, LLC | 198,182 | 2,646,000 | 0.30% | ||
| 41 | WELLS FARGO & COMPANY/MN | 193,810 | 2,587,000 | 0.30% | ||
| 42 | TIAA CREF INVESTMENT MANAGEMENT LLC | 173,404 | 2,315,000 | 0.26% | ||
| 43 | ACADIAN ASSET MANAGEMENT LLC | 164,613 | 2,199,000 | 0.25% | ||
| 44 | HBK INVESTMENTS L P | 161,800 | 2,160,000 | 0.25% | ||
| 45 | RUSSELL INVESTMENTS GROUP, LTD. | 160,960 | 2,148,000 | 0.25% | ||
| 46 | PICTET ASSET MANAGEMENT LTD | 149,029 | 1,990,000 | 0.23% | ||
| 47 | TWO SIGMA ADVISERS, LP | 133,090 | 1,777,000 | 0.20% | ||
| 48 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 130,300 | 1,740,000 | 0.20% | ||
| 49 | RHUMBLINE ADVISERS | 129,087 | 1,723,000 | 0.20% | ||
| 50 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 127,976 | 1,708,000 | 0.20% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
