| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | NEA Management Company, LLC | 3,220,433 | 32,365,000 | 21.24% | ||
| 2 | ORBIMED ADVISORS LLC | 3,220,429 | 32,365,000 | 21.24% | ||
| 3 | TPG Group Holdings (SBS) Advisors, Inc. | 2,989,282 | 30,042,000 | 19.71% | ||
| 4 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 1,535,337 | 15,430,000 | 10.13% | ||
| 5 | FMR LLC | 1,467,519 | 14,748,000 | 9.68% | ||
| 6 | Aisling Capital LLC | 1,122,417 | 11,280,000 | 7.40% | ||
| 7 | Nicholas Investment Partners, LP | 308,028 | 3,096,000 | 2.03% | ||
| 8 | DRILL CRAIG A | 283,352 | 2,848,000 | 1.87% | ||
| 9 | JPMORGAN CHASE & CO | 275,200 | 2,766,000 | 1.82% | ||
| 10 | Rock Springs Capital Management LP | 250,000 | 2,513,000 | 1.65% | ||
| 11 | BlackRock Fund Advisors | 111,481 | 1,120,000 | 0.73% | ||
| 12 | Bank of New York Mellon Corp | 69,289 | 696,000 | 0.46% | ||
| 13 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 52,704 | 530,000 | 0.35% | ||
| 14 | BlackRock Institutional Trust Company, N.A. | 38,449 | 386,000 | 0.25% | ||
| 15 | GOLDMAN SACHS GROUP INC | 37,940 | 381,000 | 0.25% | ||
| 16 | NORTHERN TRUST CORP | 27,202 | 273,000 | 0.18% | ||
| 17 | STATE STREET CORP | 24,300 | 244,000 | 0.16% | ||
| 18 | Spark Investment Management LLC | 21,700 | 218,000 | 0.14% | ||
| 19 | Nationwide Fund Advisors | 17,314 | 174,000 | 0.11% | ||
| 20 | VANGUARD GROUP INC | 12,447 | 125,000 | 0.08% | ||
| 21 | BlackRock Investment Management, LLC | 11,856 | 119,000 | 0.08% | ||
| 22 | Platte River Capital LLC | 11,400 | 115,000 | 0.08% | ||
| 23 | MILLENNIUM MANAGEMENT LLC | 11,175 | 112,000 | 0.07% | ||
| 24 | GEODE CAPITAL MANAGEMENT, LLC | 10,293 | 103,000 | 0.07% | ||
| 25 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 9,300 | 93,000 | 0.06% | ||
| 26 | MORGAN STANLEY | 5,191 | 52,000 | 0.03% | ||
| 27 | TEACHERS ADVISORS, LLC | 4,681 | 47,000 | 0.03% | ||
| 28 | BANK OF AMERICA CORP /DE/ | 3,120 | 31,000 | 0.02% | ||
| 29 | Tower Research Capital LLC (TRC) | 2,882 | 29,000 | 0.02% | ||
| 30 | MANAGED ACCOUNT ADVISORS LLC | 2,809 | 28,000 | 0.02% | ||
| 31 | CITIGROUP INC | 1,714 | 17,000 | 0.01% | ||
| 32 | BLACKROCK ADVISORS LLC | 1,703 | 17,000 | 0.01% | ||
| 33 | STRS OHIO | 1,700 | 17,000 | 0.01% | ||
| 34 | WELLS FARGO & COMPANY/MN | 300 | 3,000 | 0.00% | ||
| 35 | Ground Swell Capital, LLC | 310 | 3,000 | 0.00% | ||
| 36 | DEUTSCHE BANK AG\ | 1 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
