| 1 |
WELLINGTON MANAGEMENT GROUP LLP |
3,933,597 |
50,861,000 |
17.47% |
|
|
| 2 |
JENNISON ASSOCIATES LLC |
2,763,855 |
35,737,000 |
12.27% |
|
|
| 3 |
FEDERATED HERMES, INC. |
2,313,639 |
29,915,000 |
10.28% |
|
|
| 4 |
VANGUARD GROUP INC |
848,804 |
10,975,000 |
3.77% |
|
|
| 5 |
Granahan Investment Management, LLC |
843,121 |
10,902,000 |
3.74% |
|
|
| 6 |
MILLENNIUM MANAGEMENT LLC |
773,639 |
10,003,000 |
3.44% |
|
|
| 7 |
Broadfin Capital, LLC |
710,600 |
9,188,000 |
3.16% |
|
|
| 8 |
BlackRock Fund Advisors |
661,629 |
8,555,000 |
2.94% |
|
|
| 9 |
KOPP INVESTMENT ADVISORS LLC |
645,078 |
8,341,000 |
2.86% |
|
|
| 10 |
BlackRock Institutional Trust Company, N.A. |
563,729 |
7,289,000 |
2.50% |
|
|
| 11 |
ROYCE & ASSOCIATES LP |
533,800 |
6,902,000 |
2.37% |
|
|
| 12 |
MORGAN STANLEY |
482,579 |
6,240,000 |
2.14% |
|
|
| 13 |
Aisling Capital LLC |
450,000 |
5,819,000 |
2.00% |
|
|
| 14 |
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
422,368 |
5,461,000 |
1.88% |
|
|
| 15 |
STATE STREET CORP |
380,784 |
4,923,000 |
1.69% |
|
|
| 16 |
THRIVENT FINANCIAL FOR LUTHERANS |
355,353 |
4,595,000 |
1.58% |
|
|
| 17 |
NORTHERN TRUST CORP |
348,431 |
4,506,000 |
1.55% |
|
|
| 18 |
Rock Springs Capital Management LP |
340,000 |
4,396,000 |
1.51% |
|
|
| 19 |
SCHRODER INVESTMENT MANAGEMENT GROUP |
304,200 |
3,933,000 |
1.35% |
|
|
| 20 |
WADDELL & REED FINANCIAL INC |
291,000 |
3,763,000 |
1.29% |
|
|
| 21 |
PURA VIDA INVESTMENTS, LLC |
215,000 |
2,780,000 |
0.95% |
|
|
| 22 |
BELLEVUE GROUP AG |
205,325 |
2,655,000 |
0.91% |
|
|
| 23 |
GOLDMAN SACHS GROUP INC |
200,000 |
2,586,000 |
0.89% |
Call |
|
| 24 |
SECTORAL ASSET MANAGEMENT INC |
193,140 |
2,497,000 |
0.86% |
|
|
| 25 |
ADAGE CAPITAL PARTNERS GP, L.L.C. |
174,351 |
2,254,000 |
0.77% |
|
|
| 26 |
KORNITZER CAPITAL MANAGEMENT INC /KS |
169,100 |
2,186,000 |
0.75% |
|
|
| 27 |
UNITED SERVICES AUTOMOBILE ASSOCIATION |
164,031 |
2,121,000 |
0.73% |
|
|
| 28 |
Allianz Asset Management GmbH |
155,938 |
2,016,000 |
0.69% |
|
|
| 29 |
Iguana Healthcare Management, LLC |
150,000 |
1,940,000 |
0.67% |
|
|
| 30 |
JPMORGAN CHASE & CO |
146,649 |
1,896,000 |
0.65% |
|
|
| 31 |
GEODE CAPITAL MANAGEMENT, LLC |
142,052 |
1,836,000 |
0.63% |
|
|
| 32 |
BANK OF AMERICA CORP /DE/ |
126,377 |
1,634,000 |
0.56% |
|
|
| 33 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
117,905 |
1,525,000 |
0.52% |
|
|
| 34 |
Penn Capital Management Company, LLC |
110,894 |
1,434,000 |
0.49% |
|
|
| 35 |
PURA VIDA INVESTMENTS, LLC |
100,000 |
1,293,000 |
0.44% |
Call |
|
| 36 |
BlackRock Investment Management, LLC |
98,668 |
1,276,000 |
0.44% |
|
|
| 37 |
WELLS FARGO & COMPANY/MN |
96,393 |
1,247,000 |
0.43% |
|
|
| 38 |
TFS CAPITAL LLC |
94,674 |
1,224,000 |
0.42% |
|
|
| 39 |
DEUTSCHE BANK AG\ |
93,394 |
1,206,000 |
0.41% |
|
|
| 40 |
Bank of New York Mellon Corp |
92,733 |
1,199,000 |
0.41% |
|
|
| 41 |
MENTA CAPITAL LLC |
92,541 |
1,197,000 |
0.41% |
|
|
| 42 |
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC |
91,711 |
1,186,000 |
0.41% |
|
|
| 43 |
RAYMOND JAMES & ASSOCIATES |
88,125 |
1,139,000 |
0.39% |
|
|
| 44 |
Granite Point Capital Management, L.P. |
81,475 |
1,053,000 |
0.36% |
|
|
| 45 |
BLAIR WILLIAM & CO/IL |
72,882 |
942,000 |
0.32% |
|
|
| 46 |
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
70,000 |
905,000 |
0.31% |
|
|
| 47 |
CITADEL ADVISORS LLC |
68,184 |
882,000 |
0.30% |
|
|
| 48 |
QS Investors, LLC |
67,950 |
879,000 |
0.30% |
|
|
| 49 |
WELCH CAPITAL PARTNERS LLC/NY |
66,084 |
854,000 |
0.29% |
|
|
| 50 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
65,748 |
851,000 |
0.29% |
|
|
