| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | NEA Management Company, LLC | 2,546,843 | 7,411,000 | 37.67% | ||
| 2 | GREAT POINT PARTNERS LLC | 2,457,144 | 7,187,000 | 36.53% | ||
| 3 | BAKER BROS. ADVISORS LP | 711,499 | 2,082,000 | 10.58% | ||
| 4 | EverPoint Asset Management, LLC | 600,000 | 1,746,000 | 8.88% | ||
| 5 | MILLENNIUM MANAGEMENT LLC | 145,200 | 423,000 | 2.15% | ||
| 6 | Lombard Odier Asset Management (USA) Corp | 99,481 | 292,000 | 1.48% | ||
| 7 | Abingworth LLP | 88,307 | 256,000 | 1.30% | ||
| 8 | RENAISSANCE TECHNOLOGIES LLC | 30,400 | 88,000 | 0.45% | ||
| 9 | GOLDMAN SACHS GROUP INC | 21,118 | 61,000 | 0.31% | ||
| 10 | Redmile Group, LLC | 19,710 | 58,000 | 0.29% | ||
| 11 | ROYAL BANK OF CANADA | 10,823 | 31,000 | 0.16% | ||
| 12 | BANK OF MONTREAL /CAN/ | 7,500 | 22,000 | 0.11% | ||
| 13 | UBS Group AG | 2,019 | 6,000 | 0.03% | ||
| 14 | MORGAN STANLEY | 2,155 | 6,000 | 0.03% | ||
| 15 | BANK OF AMERICA CORP /DE/ | 1,000 | 3,000 | 0.02% | ||
| 16 | Tower Research Capital LLC (TRC) | 300 | 1,000 | 0.01% | ||
| 17 | TORONTO DOMINION BANK | 36 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.