| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | GREAT POINT PARTNERS LLC | 2,457,144 | 7,192,000 | 35.79% | ||
| 2 | NEA Management Company, LLC | 2,546,843 | 7,055,000 | 35.11% | ||
| 3 | BAKER BROS. ADVISORS LP | 711,499 | 2,120,000 | 10.55% | ||
| 4 | EverPoint Asset Management, LLC | 600,000 | 1,662,000 | 8.27% | ||
| 5 | Abingworth LLP | 512,036 | 1,388,000 | 6.91% | ||
| 6 | Lombard Odier Asset Management (USA) Corp | 102,294 | 283,000 | 1.41% | ||
| 7 | MILLENNIUM MANAGEMENT LLC | 50,000 | 139,000 | 0.69% | ||
| 8 | RENAISSANCE TECHNOLOGIES LLC | 41,100 | 114,000 | 0.57% | ||
| 9 | Redmile Group, LLC | 28,410 | 79,000 | 0.39% | ||
| 10 | ROYAL BANK OF CANADA | 10,768 | 30,000 | 0.15% | ||
| 11 | BANK OF MONTREAL /CAN/ | 7,500 | 21,000 | 0.10% | ||
| 12 | MORGAN STANLEY | 2,099 | 6,000 | 0.03% | ||
| 13 | Tower Research Capital LLC (TRC) | 1,000 | 4,000 | 0.02% | ||
| 14 | TORONTO DOMINION BANK | 13 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
