| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | NORTH TIDE CAPITAL, LLC | 1,800,000 | 54,108,000 | 10.23% | ||
| 2 | Consonance Capital Management LP | 1,436,495 | 43,181,000 | 8.17% | ||
| 3 | Camber Capital Management LP | 1,250,000 | 37,575,000 | 7.11% | ||
| 4 | VANGUARD GROUP INC | 1,193,072 | 35,863,000 | 6.78% | ||
| 5 | SEGALL BRYANT & HAMILL, LLC | 929,697 | 27,947,000 | 5.28% | ||
| 6 | SNYDER CAPITAL MANAGEMENT L P | 848,773 | 25,514,000 | 4.82% | ||
| 7 | BlackRock Institutional Trust Company, N.A. | 774,546 | 23,283,000 | 4.40% | ||
| 8 | DIMENSIONAL FUND ADVISORS LP | 678,200 | 20,387,000 | 3.86% | ||
| 9 | DIAMOND HILL CAPITAL MANAGEMENT INC | 566,586 | 17,032,000 | 3.22% | ||
| 10 | DEERFIELD MANAGEMENT COMPANY, L.P. | 533,812 | 16,046,000 | 3.03% | ||
| 11 | BlackRock Fund Advisors | 457,248 | 13,745,000 | 2.60% | ||
| 12 | AJO, LP | 430,700 | 12,947,000 | 2.45% | ||
| 13 | Numeric Investors LLC | 420,160 | 12,630,000 | 2.39% | ||
| 14 | STATE STREET CORP | 326,132 | 9,801,000 | 1.85% | ||
| 15 | Krensavage Asset Management, LLC | 312,470 | 9,393,000 | 1.78% | ||
| 16 | SENZAR ASSET MANAGEMENT, LLC | 306,898 | 9,225,000 | 1.74% | ||
| 17 | AQR CAPITAL MANAGEMENT LLC | 274,188 | 8,242,000 | 1.56% | ||
| 18 | AMERIPRISE FINANCIAL INC | 270,297 | 8,125,000 | 1.54% | ||
| 19 | D. E. Shaw & Co., Inc. | 263,158 | 7,911,000 | 1.50% | ||
| 20 | NORGES BANK | 256,049 | 7,697,000 | 1.46% | ||
| 21 | NORTHERN TRUST CORP | 246,750 | 7,417,000 | 1.40% | ||
| 22 | LSV ASSET MANAGEMENT | 202,660 | 6,091,000 | 1.15% | ||
| 23 | AMERICAN CENTURY COMPANIES INC | 182,425 | 5,484,000 | 1.04% | ||
| 24 | KENNEDY CAPITAL MANAGEMENT LLC | 181,989 | 5,471,000 | 1.03% | ||
| 25 | GABELLI FUNDS LLC | 170,432 | 5,123,000 | 0.97% | ||
| 26 | Adirondack Research & Management Inc. | 163,586 | 4,917,000 | 0.93% | ||
| 27 | RENAISSANCE TECHNOLOGIES LLC | 142,887 | 4,295,000 | 0.81% | ||
| 28 | GEODE CAPITAL MANAGEMENT, LLC | 116,769 | 3,509,000 | 0.66% | ||
| 29 | GREAT POINT PARTNERS LLC | 110,000 | 3,307,000 | 0.63% | ||
| 30 | JPMORGAN CHASE & CO | 106,275 | 3,195,000 | 0.60% | ||
| 31 | MORGAN STANLEY | 103,040 | 3,098,000 | 0.59% | ||
| 32 | RUSSELL FRANK CO/ | 97,798 | 2,996,000 | 0.57% | ||
| 33 | Bank of New York Mellon Corp | 99,642 | 2,995,000 | 0.57% | ||
| 34 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 93,800 | 2,954,000 | 0.56% | ||
| 35 | GAMCO INVESTORS, INC. ET AL | 96,625 | 2,905,000 | 0.55% | ||
| 36 | MILLENNIUM MANAGEMENT LLC | 91,132 | 2,739,000 | 0.52% | ||
| 37 | BOGLE INVESTMENT MANAGEMENT L P /DE/ | 87,351 | 2,625,000 | 0.50% | ||
| 38 | WELLINGTON MANAGEMENT GROUP LLP | 86,381 | 2,596,000 | 0.49% | ||
| 39 | GOLDMAN SACHS GROUP INC | 85,208 | 2,562,000 | 0.48% | ||
| 40 | Sio Capital Management, LLC | 78,007 | 2,345,000 | 0.44% | ||
| 41 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 77,194 | 2,321,000 | 0.44% | ||
| 42 | TIAA CREF INVESTMENT MANAGEMENT LLC | 74,959 | 2,253,000 | 0.43% | ||
| 43 | ACUTA CAPITAL PARTNERS, LLC | 67,058 | 2,016,000 | 0.38% | ||
| 44 | TWO SIGMA ADVISERS, LP | 65,574 | 1,971,000 | 0.37% | ||
| 45 | JACOBS LEVY EQUITY MANAGEMENT, INC | 63,876 | 1,920,000 | 0.36% | ||
| 46 | TWO SIGMA INVESTMENTS, LP | 61,245 | 1,841,000 | 0.35% | ||
| 47 | BlackRock Investment Management, LLC | 57,757 | 1,736,000 | 0.33% | ||
| 48 | ROYCE & ASSOCIATES LP | 56,000 | 1,683,000 | 0.32% | ||
| 49 | GSA CAPITAL PARTNERS LLP | 53,644 | 1,613,000 | 0.31% | ||
| 50 | MARTINGALE ASSET MANAGEMENT L P | 51,372 | 1,545,000 | 0.29% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
