| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FRANKLIN RESOURCES INC | 2,989,568 | 47,566,000 | 11.39% | ||
| 2 | BlackRock Fund Advisors | 2,272,375 | 36,153,000 | 8.66% | ||
| 3 | VANGUARD GROUP INC | 1,756,675 | 27,949,000 | 6.69% | ||
| 4 | HealthCor Management, L.P. | 1,750,000 | 27,843,000 | 6.67% | ||
| 5 | EverPoint Asset Management, LLC | 1,400,000 | 22,274,000 | 5.33% | ||
| 6 | Penn Capital Management Company, LLC | 1,399,205 | 22,261,000 | 5.33% | ||
| 7 | EAGLE ASSET MANAGEMENT INC | 1,006,183 | 16,008,000 | 3.83% | ||
| 8 | SECTORAL ASSET MANAGEMENT INC | 810,362 | 12,893,000 | 3.09% | ||
| 9 | MILLENNIUM MANAGEMENT LLC | 703,536 | 11,193,000 | 2.68% | ||
| 10 | JPMORGAN CHASE & CO | 698,894 | 11,119,000 | 2.66% | ||
| 11 | STATE STREET CORP | 696,322 | 11,079,000 | 2.65% | ||
| 12 | DIMENSIONAL FUND ADVISORS LP | 695,669 | 11,068,000 | 2.65% | ||
| 13 | THB ASSET MANAGEMENT | 615,546 | 9,793,000 | 2.34% | ||
| 14 | BlackRock Institutional Trust Company, N.A. | 599,906 | 9,545,000 | 2.29% | ||
| 15 | STONEPINE CAPITAL MANAGEMENT, LLC | 462,824 | 7,364,000 | 1.76% | ||
| 16 | TAMARACK ADVISERS, LP | 450,000 | 7,160,000 | 1.71% | ||
| 17 | SKANDINAVISKA ENSKILDA BANKEN AB (PUBL) | 398,900 | 6,323,000 | 1.51% | ||
| 18 | NORTHERN TRUST CORP | 371,865 | 5,916,000 | 1.42% | ||
| 19 | ALTRINSIC GLOBAL ADVISORS LLC | 331,100 | 5,268,000 | 1.26% | ||
| 20 | Tekla Capital Management LLC | 286,650 | 4,561,000 | 1.09% | ||
| 21 | TEACHERS ADVISORS, LLC | 285,150 | 4,537,000 | 1.09% | ||
| 22 | Bank of New York Mellon Corp | 266,693 | 4,243,000 | 1.02% | ||
| 23 | KENNEDY CAPITAL MANAGEMENT LLC | 262,204 | 4,172,000 | 1.00% | ||
| 24 | PRUDENTIAL FINANCIAL INC | 234,399 | 3,729,000 | 0.89% | ||
| 25 | NEW YORK STATE COMMON RETIREMENT FUND | 232,271 | 3,695,000 | 0.88% | ||
| 26 | ACADIAN ASSET MANAGEMENT LLC | 232,178 | 3,694,000 | 0.88% | ||
| 27 | FMR LLC | 228,860 | 3,642,000 | 0.87% | ||
| 28 | FOLGER HILL ASSET MANAGEMENT LP | 226,583 | 3,605,000 | 0.86% | ||
| 29 | RUSSELL FRANK CO/ | 222,133 | 3,520,000 | 0.84% | ||
| 30 | MACKENZIE FINANCIAL CORP | 200,554 | 3,191,000 | 0.76% | ||
| 31 | Point72 Asset Management, L.P. | 191,600 | 3,048,000 | 0.73% | ||
| 32 | DEUTSCHE BANK AG\ | 184,137 | 2,927,000 | 0.70% | ||
| 33 | PRINCIPAL FINANCIAL GROUP INC | 157,538 | 2,506,000 | 0.60% | ||
| 34 | MORGAN STANLEY | 155,915 | 2,480,000 | 0.59% | ||
| 35 | GEODE CAPITAL MANAGEMENT, LLC | 151,738 | 2,414,000 | 0.58% | ||
| 36 | Rhenman & Partners Asset Management AB | 150,000 | 2,387,000 | 0.57% | ||
| 37 | RAYMOND JAMES & ASSOCIATES | 148,397 | 2,361,000 | 0.57% | ||
| 38 | TFS CAPITAL LLC | 147,265 | 2,343,000 | 0.56% | ||
| 39 | ACUTA CAPITAL PARTNERS, LLC | 144,667 | 2,302,000 | 0.55% | ||
| 40 | Piermont Capital Management Inc. | 139,020 | 2,212,000 | 0.53% | ||
| 41 | GUGGENHEIM CAPITAL LLC | 135,184 | 2,151,000 | 0.51% | ||
| 42 | GOLDMAN SACHS GROUP INC | 116,356 | 1,851,000 | 0.44% | ||
| 43 | PICTET ASSET MANAGEMENT LTD | 112,200 | 1,785,000 | 0.43% | ||
| 44 | AMERIPRISE FINANCIAL INC | 110,059 | 1,751,000 | 0.42% | ||
| 45 | RICE HALL JAMES & ASSOCIATES, LLC | 103,230 | 1,642,000 | 0.39% | ||
| 46 | JW Asset Management, LLC | 101,630 | 1,617,000 | 0.39% | ||
| 47 | Invesco Ltd. | 99,835 | 1,589,000 | 0.38% | ||
| 48 | PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO | 92,043 | 1,464,000 | 0.35% | ||
| 49 | BlackRock Investment Management, LLC | 85,805 | 1,365,000 | 0.33% | ||
| 50 | WHITEBOX ADVISORS LLC | 78,572 | 1,250,000 | 0.30% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
