Dark
Light
System
Institutional Investment Manager
Tekla Capital Management LLC
Tekla Capital Management LLC (CIK: 0001300336) incorporated in Delaware, located at 100 Federal Street, Boston, MA. Institutional holdings reported to the SEC.

Institutional Holdings (2015Q4)
Portfolio Summary: 134 holdings with a total value of $2,757,591,000.
#
Name
Shares
Value ($)
%
Options
Notes
1 GILEAD SCIENCES INC 2,331,231 235,897,000 8.55%
2 CELGENE CORP 1,713,634 205,225,000 7.44%
3 BIOGEN INC 450,533 138,021,000 5.01%
4 VERTEX PHARMACEUT 1,033,503 130,046,000 4.72%
5 ALLERGAN PLC 409,586 127,996,000 4.64%
6 ALEXION PHARMACEUTIC 636,805 121,471,000 4.40%
7 JOHNSON & JOHNSON 940,988 96,658,000 3.51%
8 INCYTE 880,461 95,486,000 3.46%
9 TEVA PHARMACEUTICAL INDS LTD 1,334,237 87,579,000 3.18%
10 REGENERON PHARMACEUTICALS 154,266 83,746,000 3.04%
11 ILLUMINA INC 434,341 83,370,000 3.02%
12 BIOMARIN 596,145 62,452,000 2.26%
13 PFIZER INC 1,802,291 58,178,000 2.11%
14 AMGEN INC 321,640 52,212,000 1.89%
15 UNITEDHEALTH GROUP INC 409,100 48,127,000 1.75%
16 ALKERMES PLC SHS 510,444 40,519,000 1.47%
17 MERCK & CO INC 681,097 35,976,000 1.30%
18 SHIRE PLC 171,813 35,222,000 1.28%
19 MEDIVATION INC 667,300 32,257,000 1.17%
20 AGILENT TECHNOLOGIES INC 728,650 30,465,000 1.10%
21 HCA HOLDINGS INC 448,488 30,331,000 1.10%
22 MYLAN N V 531,252 28,725,000 1.04%
23 HUMANA 129,300 23,081,000 0.84%
24 ACADIA PHARMACEUTICALS INC COM 637,500 22,727,000 0.82%
25 MOLINA HEALTHCARE INC 347,901 20,919,000 0.76%
26 VENTAS INC 369,266 20,838,000 0.76%
27 PHYSICIANS RLTY TR 1,230,772 20,751,000 0.75%
28 PUMA BIOTECHNOLOGY 260,200 20,400,000 0.74%
29 ISHARES TR 57,670 19,511,000 0.71%
30 MEDICAL PPTYS TRUST INC 1,564,060 18,002,000 0.65%
31 NEUROCRINE BIOSCIE COM USD0.001 311,460 17,619,000 0.64%
32 ENDO INTL 286,348 17,530,000 0.64%
33 NOVO-NORDISK A S 294,600 17,110,000 0.62%
34 MCKESSON CORP 82,862 16,343,000 0.59%
35 HORIZON PHARMA PLC 749,900 16,250,000 0.59%
36 ST JUDE 255,810 15,801,000 0.57%
37 MEDICINES CO 401,970 15,010,000 0.54%
38 IMPAX LABORATORIES INC 344,683 14,739,000 0.53%
39 UNITED THERAPEUTICS 93,100 14,580,000 0.53%
40 PARATEK PHARMACEUTICALS INC 762,581 14,466,000 0.52%
41 OMEGA HEALTHCARE INVS INC 413,116 14,451,000 0.52%
42 BRISTOL MYERS SQUIBB CO 202,600 13,937,000 0.51%
43 CORSICANTO LTD 14,700,000 13,304,000 0.48% PRN
44 SANOFI 305,000 13,008,000 0.47%
45 ALNYLAM PHARMACEUTICALS INC 137,495 12,944,000 0.47%
46 BAXALTA INC 319,600 12,474,000 0.45%
47 Anacor Pharmaceuticals Inc 110,038 12,431,000 0.45%
48 THERMO FISHER SCIENTIFIC INC 86,395 12,255,000 0.44%
49 BAXTER INTL INC 319,600 12,193,000 0.44%
50 CEPHEID 333,590 12,186,000 0.44%
Page 1 of 3

Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001104659-16-094941, filed 2016.02.09).

From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.