| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 12,834,080 | 712,163,000 | 17.01% | ||
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 11,971,783 | 664,314,000 | 15.87% | ||
| 3 | VANGUARD GROUP INC | 5,385,509 | 298,843,000 | 7.14% | ||
| 4 | PRICE T ROWE ASSOCIATES INC /MD/ | 3,996,142 | 221,746,000 | 5.30% | ||
| 5 | BAILLIE GIFFORD & CO | 3,390,252 | 188,125,000 | 4.49% | ||
| 6 | DODGE & COX | 2,516,669 | 139,650,000 | 3.34% | ||
| 7 | STATE STREET CORP | 2,195,504 | 121,832,000 | 2.91% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 1,926,330 | 106,892,000 | 2.55% | ||
| 9 | BlackRock Fund Advisors | 1,870,882 | 103,815,000 | 2.48% | ||
| 10 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,662,882 | 92,273,000 | 2.20% | ||
| 11 | GILDER GAGNON HOWE & CO LLC | 1,393,947 | 77,350,000 | 1.85% | ||
| 12 | Blue Ridge Capital, L.L.C. | 1,320,000 | 73,247,000 | 1.75% | ||
| 13 | BB BIOTECH AG | 1,191,338 | 66,107,000 | 1.58% | ||
| 14 | Slate Path Capital LP | 1,135,000 | 62,981,000 | 1.50% | ||
| 15 | JENNISON ASSOCIATES LLC | 975,425 | 54,126,000 | 1.29% | ||
| 16 | MORGAN STANLEY | 875,104 | 48,559,000 | 1.16% | ||
| 17 | RTW INVESTMENTS, LP | 832,549 | 46,198,000 | 1.10% | ||
| 18 | Artal Group S.A. | 710,000 | 39,398,000 | 0.94% | ||
| 19 | 12 West Capital Management LP | 700,000 | 38,843,000 | 0.93% | ||
| 20 | WELLS FARGO & COMPANY/MN | 698,398 | 38,753,000 | 0.93% | ||
| 21 | GOLDMAN SACHS GROUP INC | 693,168 | 38,464,000 | 0.92% | ||
| 22 | BRIDGER MANAGEMENT, LLC | 687,009 | 38,122,000 | 0.91% | ||
| 23 | FRANKLIN RESOURCES INC | 592,000 | 32,850,000 | 0.78% | ||
| 24 | Capital World Investors | 573,700 | 31,835,000 | 0.76% | ||
| 25 | BlackRock Group LTD | 557,458 | 30,933,000 | 0.74% | ||
| 26 | GEODE CAPITAL MANAGEMENT, LLC | 499,616 | 27,710,000 | 0.66% | ||
| 27 | Alpha Wave Global, LP | 491,713 | 27,285,000 | 0.65% | ||
| 28 | Mitsubishi UFJ Trust & Banking Corp | 469,756 | 26,067,000 | 0.62% | ||
| 29 | NORGES BANK | 460,761 | 25,568,000 | 0.61% | ||
| 30 | FIRST TRUST ADVISORS LP | 417,247 | 23,153,000 | 0.55% | ||
| 31 | DEUTSCHE BANK AG\ | 392,751 | 21,790,000 | 0.52% | ||
| 32 | BLACKROCK ADVISORS LLC | 372,668 | 20,679,000 | 0.49% | ||
| 33 | ArrowMark Colorado Holdings LLC | 371,550 | 20,617,000 | 0.49% | ||
| 34 | NORTHERN TRUST CORP | 364,375 | 20,218,000 | 0.48% | ||
| 35 | JANUS HENDERSON INVESTORS US LLC | 358,122 | 19,871,000 | 0.47% | ||
| 36 | Bank of New York Mellon Corp | 348,636 | 19,345,000 | 0.46% | ||
| 37 | DEERFIELD MANAGEMENT COMPANY, L.P. | 336,000 | 18,645,000 | 0.45% | ||
| 38 | ZIFF BROTHERS INVESTMENTS, L.L.C. | 333,566 | 18,493,000 | 0.44% | ||
| 39 | GOLDMAN SACHS GROUP INC | 327,600 | 18,179,000 | 0.43% | Call | |
| 40 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 320,500 | 17,785,000 | 0.42% | Call | |
| 41 | Artal Group S.A. | 300,000 | 16,647,000 | 0.40% | Call | |
| 42 | Legal & General Group Plc | 296,942 | 16,477,000 | 0.39% | ||
| 43 | WESTFIELD CAPITAL MANAGEMENT CO LP | 276,767 | 15,358,000 | 0.37% | ||
| 44 | Tekla Capital Management LLC | 243,995 | 13,539,000 | 0.32% | ||
| 45 | NEW YORK STATE COMMON RETIREMENT FUND | 229,977 | 12,761,000 | 0.30% | ||
| 46 | Artisan Partners Limited Partnership | 225,203 | 12,497,000 | 0.30% | ||
| 47 | Swiss National Bank | 214,900 | 11,925,000 | 0.28% | ||
| 48 | CREDIT SUISSE AG/ | 209,295 | 11,614,000 | 0.28% | ||
| 49 | Cormorant Asset Management, LP | 200,355 | 11,118,000 | 0.27% | ||
| 50 | Sumitomo Mitsui Trust Group, Inc. | 199,354 | 11,062,000 | 0.26% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
