| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 12,872,080 | 481,931,000 | 15.85% | ||
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 12,009,971 | 449,654,000 | 14.78% | ||
| 3 | DODGE & COX | 9,204,950 | 344,633,000 | 11.33% | ||
| 4 | VANGUARD GROUP INC | 5,459,323 | 204,396,000 | 6.72% | ||
| 5 | PRICE T ROWE ASSOCIATES INC /MD/ | 4,163,714 | 155,889,000 | 5.13% | ||
| 6 | BAILLIE GIFFORD & CO | 3,318,022 | 124,227,000 | 4.08% | ||
| 7 | STATE STREET CORP | 2,361,998 | 88,430,000 | 2.91% | ||
| 8 | BlackRock Fund Advisors | 2,100,902 | 78,658,000 | 2.59% | ||
| 9 | Slate Path Capital LP | 2,000,000 | 74,880,000 | 2.46% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 1,953,854 | 73,152,000 | 2.41% | ||
| 11 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,667,426 | 62,429,000 | 2.05% | ||
| 12 | Blue Ridge Capital, L.L.C. | 1,320,000 | 49,421,000 | 1.62% | ||
| 13 | GILDER GAGNON HOWE & CO LLC | 1,230,794 | 46,081,000 | 1.52% | ||
| 14 | BB BIOTECH AG | 1,191,338 | 44,604,000 | 1.47% | ||
| 15 | GOLDMAN SACHS GROUP INC | 914,437 | 34,237,000 | 1.13% | ||
| 16 | MORGAN STANLEY | 812,184 | 30,408,000 | 1.00% | ||
| 17 | RTW INVESTMENTS, LP | 789,208 | 29,548,000 | 0.97% | ||
| 18 | FIRST TRUST ADVISORS LP | 738,408 | 27,646,000 | 0.91% | ||
| 19 | BRIDGER MANAGEMENT, LLC | 718,615 | 26,905,000 | 0.88% | ||
| 20 | 12 West Capital Management LP | 700,000 | 26,208,000 | 0.86% | ||
| 21 | ArrowMark Colorado Holdings LLC | 692,736 | 25,936,000 | 0.85% | ||
| 22 | NORGES BANK | 664,663 | 24,885,000 | 0.82% | ||
| 23 | GEODE CAPITAL MANAGEMENT, LLC | 534,016 | 19,993,000 | 0.66% | ||
| 24 | FRANKLIN RESOURCES INC | 520,417 | 19,484,000 | 0.64% | ||
| 25 | JANUS HENDERSON INVESTORS US LLC | 517,430 | 19,375,000 | 0.64% | ||
| 26 | Artal Group S.A. | 500,000 | 18,720,000 | 0.62% | ||
| 27 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 433,100 | 16,215,000 | 0.53% | Put | |
| 28 | NORTHERN TRUST CORP | 345,959 | 12,952,000 | 0.43% | ||
| 29 | BALYASNY ASSET MANAGEMENT L.P. | 342,822 | 12,835,000 | 0.42% | ||
| 30 | PICTET ASSET MANAGEMENT LTD | 327,392 | 12,258,000 | 0.40% | ||
| 31 | DEUTSCHE BANK AG\ | 320,988 | 12,015,000 | 0.40% | ||
| 32 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 320,700 | 12,007,000 | 0.39% | Call | |
| 33 | Bank of New York Mellon Corp | 302,783 | 11,336,000 | 0.37% | ||
| 34 | Mitsubishi UFJ Trust & Banking Corp | 290,157 | 10,863,000 | 0.36% | ||
| 35 | WELLS FARGO & COMPANY/MN | 279,749 | 10,473,000 | 0.34% | ||
| 36 | 683 Capital Management, LLC | 270,000 | 10,109,000 | 0.33% | ||
| 37 | BOXER CAPITAL, LLC | 250,000 | 9,360,000 | 0.31% | ||
| 38 | Legal & General Group Plc | 247,367 | 9,261,000 | 0.30% | ||
| 39 | Tekla Capital Management LLC | 243,995 | 9,135,000 | 0.30% | ||
| 40 | BlackRock Group LTD | 237,918 | 8,908,000 | 0.29% | ||
| 41 | FRONTIER CAPITAL MANAGEMENT CO LLC | 236,935 | 8,871,000 | 0.29% | ||
| 42 | MILLENNIUM MANAGEMENT LLC | 229,240 | 8,583,000 | 0.28% | ||
| 43 | D. E. Shaw & Co., Inc. | 215,426 | 8,065,000 | 0.27% | ||
| 44 | TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 211,069 | 7,902,000 | 0.26% | ||
| 45 | CIBC WORLD MARKETS CORP | 210,000 | 7,862,000 | 0.26% | ||
| 46 | PEREGRINE CAPITAL MANAGEMENT INC /MN/ | 206,432 | 7,729,000 | 0.25% | ||
| 47 | Artal Group S.A. | 200,000 | 7,488,000 | 0.25% | Call | |
| 48 | TimesSquare Capital Management, LLC | 198,800 | 7,443,000 | 0.24% | ||
| 49 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 192,542 | 7,209,000 | 0.24% | ||
| 50 | NEW YORK STATE COMMON RETIREMENT FUND | 179,854 | 6,734,000 | 0.22% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
