| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 6,366,185 | 190,031,000 | 9.01% | ||
| 2 | DEERFIELD MANAGEMENT COMPANY, L.P. | 6,267,382 | 187,081,000 | 8.87% | ||
| 3 | Palo Alto Investors LP | 4,854,631 | 144,911,000 | 6.87% | ||
| 4 | PAULSON & CO. INC. | 4,000,000 | 119,400,000 | 5.66% | ||
| 5 | VANGUARD GROUP INC | 3,015,490 | 90,013,000 | 4.27% | ||
| 6 | TIG Advisors, LLC | 2,799,913 | 83,577,000 | 3.96% | ||
| 7 | Invesco Ltd. | 2,690,116 | 80,300,000 | 3.81% | ||
| 8 | Artal Group S.A. | 2,275,000 | 67,909,000 | 3.22% | Call | |
| 9 | STATE STREET CORP | 2,244,858 | 67,014,000 | 3.18% | ||
| 10 | BARCLAYS PLC | 2,253,942 | 65,364,000 | 3.10% | ||
| 11 | JET CAPITAL INVESTORS L P | 2,100,000 | 62,685,000 | 2.97% | ||
| 12 | WELLINGTON MANAGEMENT GROUP LLP | 2,080,848 | 62,114,000 | 2.94% | ||
| 13 | BlackRock Fund Advisors | 2,072,026 | 61,850,000 | 2.93% | ||
| 14 | Clearbridge Investments, LLC | 1,582,948 | 47,251,000 | 2.24% | ||
| 15 | Consonance Capital Management LP | 1,493,560 | 44,583,000 | 2.11% | ||
| 16 | BlackRock Institutional Trust Company, N.A. | 1,355,693 | 40,467,000 | 1.92% | ||
| 17 | TimesSquare Capital Management, LLC | 1,222,595 | 36,494,000 | 1.73% | ||
| 18 | York Capital Management Global Advisors, LLC | 1,000,000 | 29,850,000 | 1.41% | ||
| 19 | Artal Group S.A. | 1,000,000 | 29,850,000 | 1.41% | ||
| 20 | Granahan Investment Management, LLC | 972,380 | 29,026,000 | 1.38% | ||
| 21 | PUTNAM INVESTMENTS LLC | 856,669 | 25,572,000 | 1.21% | ||
| 22 | DIMENSIONAL FUND ADVISORS LP | 753,133 | 22,482,000 | 1.07% | ||
| 23 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 683,700 | 20,408,000 | 0.97% | Call | |
| 24 | FRANKLIN RESOURCES INC | 676,000 | 20,179,000 | 0.96% | ||
| 25 | Tamarack Capital Management, LLC | 650,000 | 19,403,000 | 0.92% | ||
| 26 | NORTHERN TRUST CORP | 605,642 | 18,078,000 | 0.86% | ||
| 27 | GOLDMAN SACHS GROUP INC | 587,927 | 17,550,000 | 0.83% | ||
| 28 | MORGAN STANLEY | 555,610 | 16,585,000 | 0.79% | ||
| 29 | Tiger Legatus Capital Management, LLC | 500,000 | 14,925,000 | 0.71% | ||
| 30 | EverPoint Asset Management, LLC | 500,000 | 14,925,000 | 0.71% | ||
| 31 | ANGELO GORDON & CO., L.P. | 450,000 | 13,433,000 | 0.64% | ||
| 32 | GLG Partners LP | 439,719 | 13,126,000 | 0.62% | ||
| 33 | CREDIT AGRICOLE S A | 438,177 | 13,080,000 | 0.62% | ||
| 34 | SOUTH TEXAS MONEY MANAGEMENT LTD | 432,229 | 12,902,000 | 0.61% | ||
| 35 | Antipodean Advisors LLC | 377,000 | 11,253,000 | 0.53% | ||
| 36 | Bank of New York Mellon Corp | 344,774 | 10,291,000 | 0.49% | ||
| 37 | Loeb Offshore Management LP | 312,399 | 9,325,000 | 0.44% | ||
| 38 | CREDIT SUISSE AG/ | 312,348 | 9,323,000 | 0.44% | ||
| 39 | KING INVESTMENT ADVISORS INC/TX | 282,675 | 8,438,000 | 0.40% | ||
| 40 | C WorldWide Group Holding A/S | 273,951 | 8,323,000 | 0.39% | ||
| 41 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 262,000 | 7,821,000 | 0.37% | Put | |
| 42 | SENECA CAPITAL INVESTMENTS, L.P. | 260,000 | 7,761,000 | 0.37% | ||
| 43 | Hudson Bay Capital Management LP | 259,459 | 7,745,000 | 0.37% | ||
| 44 | GEODE CAPITAL MANAGEMENT, LLC | 257,522 | 7,687,000 | 0.36% | ||
| 45 | UBS AG | 255,366 | 7,623,000 | 0.36% | ||
| 46 | TIAA CREF INVESTMENT MANAGEMENT LLC | 251,013 | 7,493,000 | 0.36% | ||
| 47 | BANK OF AMERICA CORP /DE/ | 238,530 | 7,120,000 | 0.34% | ||
| 48 | NORGES BANK | 216,279 | 6,456,000 | 0.31% | ||
| 49 | D. E. Shaw & Co., Inc. | 209,200 | 6,245,000 | 0.30% | Put | |
| 50 | Amici Capital, LLC | 200,230 | 5,977,000 | 0.28% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
