| 1 |
HealthCor Management, L.P. |
19,981,655 |
53,911,000 |
42.52% |
|
|
| 2 |
WELLINGTON MANAGEMENT GROUP LLP |
9,471,788 |
29,267,000 |
23.09% |
|
|
| 3 |
FMR LLC |
6,315,800 |
19,516,000 |
15.39% |
|
|
| 4 |
CLOUGH CAPITAL PARTNERS L P |
2,013,254 |
6,221,000 |
4.91% |
|
|
| 5 |
VANGUARD GROUP INC |
1,229,853 |
3,800,000 |
3.00% |
|
|
| 6 |
MILLENNIUM MANAGEMENT LLC |
687,759 |
2,125,000 |
1.68% |
|
|
| 7 |
GAM Holding AG |
685,211 |
2,117,000 |
1.67% |
|
|
| 8 |
GOLDMAN SACHS GROUP INC |
615,653 |
1,902,000 |
1.50% |
|
|
| 9 |
BlackRock Fund Advisors |
590,534 |
1,825,000 |
1.44% |
|
|
| 10 |
GEODE CAPITAL MANAGEMENT, LLC |
295,688 |
913,000 |
0.72% |
|
|
| 11 |
NORTHERN TRUST CORP |
248,400 |
767,000 |
0.61% |
|
|
| 12 |
EMERALD MUTUAL FUND ADVISERS TRUST |
200,000 |
618,000 |
0.49% |
|
|
| 13 |
STATE STREET CORP |
196,346 |
607,000 |
0.48% |
|
|
| 14 |
BlackRock Institutional Trust Company, N.A. |
179,940 |
556,000 |
0.44% |
|
|
| 15 |
Boston Partners |
171,256 |
529,000 |
0.42% |
|
|
| 16 |
Bank of New York Mellon Corp |
113,934 |
352,000 |
0.28% |
|
|
| 17 |
BlackRock Investment Management, LLC |
75,846 |
234,000 |
0.18% |
|
|
| 18 |
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
71,970 |
222,000 |
0.18% |
|
|
| 19 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
71,581 |
221,000 |
0.17% |
|
|
| 20 |
TFS CAPITAL LLC |
65,891 |
204,000 |
0.16% |
|
|
| 21 |
TUDOR INVESTMENT CORP ET AL |
57,827 |
179,000 |
0.14% |
|
|
| 22 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
41,012 |
127,000 |
0.10% |
|
|
| 23 |
TEACHERS ADVISORS, LLC |
34,200 |
106,000 |
0.08% |
|
|
| 24 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
25,000 |
78,000 |
0.06% |
|
|
| 25 |
NEW YORK STATE COMMON RETIREMENT FUND |
20,500 |
63,000 |
0.05% |
|
|
| 26 |
SG Americas Securities, LLC |
18,040 |
56,000 |
0.04% |
|
|
| 27 |
Nationwide Fund Advisors |
13,992 |
43,000 |
0.03% |
|
|
| 28 |
AMERICAN INTERNATIONAL GROUP, INC. |
13,206 |
41,000 |
0.03% |
|
|
| 29 |
CREDIT SUISSE AG/ |
11,918 |
37,000 |
0.03% |
|
|
| 30 |
BLACKROCK ADVISORS LLC |
11,631 |
36,000 |
0.03% |
|
|
| 31 |
RHUMBLINE ADVISERS |
11,267 |
35,000 |
0.03% |
|
|
| 32 |
DEUTSCHE BANK AG\ |
7,657 |
23,000 |
0.02% |
|
|
| 33 |
BNP PARIBAS FINANCIAL MARKETS |
4,654 |
14,381 |
0.01% |
|
|
| 34 |
UBS Group AG |
4,099 |
13,000 |
0.01% |
|
|
| 35 |
MORGAN STANLEY |
2,500 |
8,000 |
0.01% |
|
|
| 36 |
Tower Research Capital LLC (TRC) |
2,351 |
7,000 |
0.01% |
|
|
| 37 |
ROYAL BANK OF CANADA |
1,067 |
3,000 |
0.00% |
|
|
| 38 |
BARCLAYS PLC |
117 |
0 |
0.00% |
|
|
| 39 |
BANK OF AMERICA CORP /DE/ |
80 |
0 |
0.00% |
|
|
| 40 |
CITIGROUP INC |
4 |
0 |
0.00% |
|
|
| 41 |
WELLS FARGO & COMPANY/MN |
114 |
0 |
0.00% |
|
|
| 42 |
STRS OHIO |
0 |
0 |
0.00% |
|
|
