| 1 |
HEALTHCOR PARTNERS MANAGEMENT LP |
24,943,042 |
24,694,000 |
35.00% |
|
|
| 2 |
HealthCor Management, L.P. |
19,981,655 |
19,792,000 |
28.05% |
|
|
| 3 |
WELLINGTON MANAGEMENT GROUP LLP |
12,052,063 |
11,937,000 |
16.92% |
|
|
| 4 |
FMR LLC |
6,315,800 |
6,256,000 |
8.87% |
|
|
| 5 |
CLOUGH CAPITAL PARTNERS L P |
2,127,354 |
2,107,000 |
2.99% |
|
|
| 6 |
VANGUARD GROUP INC |
1,820,410 |
1,803,000 |
2.56% |
|
|
| 7 |
GAM Holding AG |
1,003,681 |
999,000 |
1.42% |
|
|
| 8 |
BlackRock Fund Advisors |
584,269 |
579,000 |
0.82% |
|
|
| 9 |
MILLENNIUM MANAGEMENT LLC |
494,027 |
489,000 |
0.69% |
|
|
| 10 |
GEODE CAPITAL MANAGEMENT, LLC |
317,670 |
314,000 |
0.45% |
|
|
| 11 |
NORTHERN TRUST CORP |
273,374 |
271,000 |
0.38% |
|
|
| 12 |
STATE STREET CORP |
230,500 |
226,000 |
0.32% |
|
|
| 13 |
BlackRock Institutional Trust Company, N.A. |
207,268 |
205,000 |
0.29% |
|
|
| 14 |
US BANCORP \DE\ |
201,042 |
199,000 |
0.28% |
|
|
| 15 |
Bank of New York Mellon Corp |
113,934 |
113,000 |
0.16% |
|
|
| 16 |
BlackRock Investment Management, LLC |
77,923 |
77,000 |
0.11% |
|
|
| 17 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
71,581 |
71,000 |
0.10% |
|
|
| 18 |
GOLDMAN SACHS GROUP INC |
62,731 |
62,000 |
0.09% |
|
|
| 19 |
TUDOR INVESTMENT CORP ET AL |
53,041 |
53,000 |
0.08% |
|
|
| 20 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
48,167 |
48,000 |
0.07% |
|
|
| 21 |
Paloma Partners Management Co |
35,115 |
35,000 |
0.05% |
|
|
| 22 |
TEACHERS ADVISORS, LLC |
34,200 |
34,000 |
0.05% |
|
|
| 23 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
25,000 |
25,000 |
0.04% |
|
|
| 24 |
NEW YORK STATE COMMON RETIREMENT FUND |
20,500 |
20,000 |
0.03% |
|
|
| 25 |
CITADEL ADVISORS LLC |
19,062 |
19,000 |
0.03% |
|
|
| 26 |
CITIGROUP INC |
18,695 |
19,000 |
0.03% |
|
|
| 27 |
RHUMBLINE ADVISERS |
18,517 |
18,000 |
0.03% |
|
|
| 28 |
BLACKROCK ADVISORS LLC |
16,469 |
16,000 |
0.02% |
|
|
| 29 |
DEUTSCHE BANK AG\ |
15,961 |
15,000 |
0.02% |
|
|
| 30 |
Nationwide Fund Advisors |
13,992 |
14,000 |
0.02% |
|
|
| 31 |
AMERICAN INTERNATIONAL GROUP, INC. |
13,183 |
13,000 |
0.02% |
|
|
| 32 |
Cetera Advisors LLC |
12,000 |
12,000 |
0.02% |
|
|
| 33 |
MORGAN STANLEY |
10,550 |
10,000 |
0.01% |
|
|
| 34 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
4,278 |
4,000 |
0.01% |
|
|
| 35 |
Tower Research Capital LLC (TRC) |
3,340 |
3,000 |
0.00% |
|
|
| 36 |
WELLS FARGO & COMPANY/MN |
1,471 |
1,000 |
0.00% |
|
|
| 37 |
BARCLAYS PLC |
48 |
0 |
0.00% |
|
|
