| 1 |
HealthCor Management, L.P. |
19,981,655 |
26,176,000 |
31.34% |
|
|
| 2 |
Consonance Capital Management LP |
15,114,872 |
19,800,000 |
23.71% |
|
|
| 3 |
HUDSON EXECUTIVE CAPITAL LP |
11,336,154 |
14,850,000 |
17.78% |
|
|
| 4 |
FMR LLC |
6,315,800 |
8,274,000 |
9.91% |
|
|
| 5 |
BlackRock Finance, Inc. |
2,323,850 |
3,046,000 |
3.65% |
|
|
| 6 |
VANGUARD GROUP INC |
2,080,801 |
2,726,000 |
3.26% |
|
|
| 7 |
WELLINGTON MANAGEMENT GROUP LLP |
920,429 |
1,206,000 |
1.44% |
|
|
| 8 |
Laurion Capital Management LP |
811,370 |
1,063,000 |
1.27% |
|
|
| 9 |
NORTHERN TRUST CORP |
674,109 |
883,000 |
1.06% |
|
|
| 10 |
GEODE CAPITAL MANAGEMENT, LLC |
673,488 |
882,000 |
1.06% |
|
|
| 11 |
STATE STREET CORP |
641,932 |
840,000 |
1.01% |
|
|
| 12 |
MORGAN STANLEY |
497,023 |
651,000 |
0.78% |
|
|
| 13 |
MILLENNIUM MANAGEMENT LLC |
447,255 |
586,000 |
0.70% |
|
|
| 14 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
390,600 |
512,000 |
0.61% |
|
|
| 15 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
285,900 |
375,000 |
0.45% |
|
|
| 16 |
US BANCORP \DE\ |
201,042 |
263,000 |
0.31% |
|
|
| 17 |
Bank of New York Mellon Corp |
163,012 |
214,000 |
0.26% |
|
|
| 18 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
129,077 |
169,000 |
0.20% |
|
|
| 19 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
110,558 |
145,000 |
0.17% |
|
|
| 20 |
BKS ADVISORS, LLC |
100,000 |
131,000 |
0.16% |
|
|
| 21 |
TEACHERS ADVISORS, LLC |
58,888 |
77,000 |
0.09% |
|
|
| 22 |
SG Americas Securities, LLC |
57,229 |
75,000 |
0.09% |
|
|
| 23 |
RHUMBLINE ADVISERS |
48,260 |
63,000 |
0.08% |
|
|
| 24 |
UBS Group AG |
41,149 |
54,000 |
0.06% |
|
|
| 25 |
TUDOR INVESTMENT CORP ET AL |
37,974 |
50,000 |
0.06% |
|
|
| 26 |
JPMORGAN CHASE & CO |
37,104 |
49,000 |
0.06% |
|
|
| 27 |
DEUTSCHE BANK AG\ |
36,733 |
47,000 |
0.06% |
|
|
| 28 |
AMERICAN INTERNATIONAL GROUP, INC. |
33,820 |
44,000 |
0.05% |
|
|
| 29 |
Nationwide Fund Advisors |
31,447 |
41,000 |
0.05% |
|
|
| 30 |
GOLDMAN SACHS GROUP INC |
23,738 |
31,000 |
0.04% |
|
|
| 31 |
GUGGENHEIM CAPITAL LLC |
22,453 |
30,000 |
0.04% |
|
|
| 32 |
NEW YORK STATE COMMON RETIREMENT FUND |
20,501 |
27,000 |
0.03% |
|
|
| 33 |
Raymond James Financial Services Advisors, Inc. |
19,500 |
26,000 |
0.03% |
|
|
| 34 |
FNY PARTNERS FUND LP |
14,710 |
19,000 |
0.02% |
|
|
| 35 |
Cetera Advisors LLC |
13,000 |
17,000 |
0.02% |
|
|
| 36 |
STEWARD PARTNERS INVESTMENT ADVISORY, LLC |
11,000 |
14,000 |
0.02% |
|
|
| 37 |
BANK OF AMERICA CORP /DE/ |
9,739 |
13,000 |
0.02% |
|
|
| 38 |
Invesco Ltd. |
10,099 |
13,000 |
0.02% |
|
|
| 39 |
Evanson Asset Management, LLC |
10,000 |
13,000 |
0.02% |
|
|
| 40 |
BENJAMIN F. EDWARDS & COMPANY, INC. |
7,000 |
9,000 |
0.01% |
|
|
| 41 |
WELLS FARGO & COMPANY/MN |
6,233 |
8,000 |
0.01% |
|
|
| 42 |
ROYAL BANK OF CANADA |
2,337 |
3,000 |
0.00% |
|
|
| 43 |
West Oak Capital, LLC |
2,150 |
2,817 |
0.00% |
|
|
| 44 |
Ameritas Investment Partners, Inc. |
1,737 |
2,000 |
0.00% |
|
|
| 45 |
MEEDER ASSET MANAGEMENT INC |
427 |
1,000 |
0.00% |
|
|
| 46 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
426 |
1,000 |
0.00% |
|
|
| 47 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
1,000 |
1,000 |
0.00% |
|
|
| 48 |
BNP PARIBAS FINANCIAL MARKETS |
361 |
473 |
0.00% |
|
|
| 49 |
BARCLAYS PLC |
283 |
0 |
0.00% |
|
|
| 50 |
CITIGROUP INC |
176 |
0 |
0.00% |
|
|
