| 1 |
PERCEPTIVE ADVISORS LLC |
3,200,000 |
9,568,000 |
31.27% |
|
|
| 2 |
Knoll Capital Management, LLC |
2,563,925 |
7,666,000 |
25.05% |
|
|
| 3 |
Cormorant Asset Management, LP |
2,000,000 |
5,980,000 |
19.54% |
|
|
| 4 |
VANGUARD GROUP INC |
654,901 |
1,958,000 |
6.40% |
|
|
| 5 |
DAFNA Capital Management LLC |
400,000 |
1,196,000 |
3.91% |
|
|
| 6 |
Ghost Tree Capital, LLC |
300,000 |
897,000 |
2.93% |
|
|
| 7 |
Raymond James Financial Services Advisors, Inc. |
264,753 |
792,000 |
2.59% |
|
|
| 8 |
BlackRock Institutional Trust Company, N.A. |
189,139 |
566,000 |
1.85% |
|
|
| 9 |
RENAISSANCE TECHNOLOGIES LLC |
146,900 |
439,000 |
1.43% |
|
|
| 10 |
GEODE CAPITAL MANAGEMENT, LLC |
143,582 |
429,000 |
1.40% |
|
|
| 11 |
Creative Planning |
123,567 |
369,000 |
1.21% |
|
|
| 12 |
BlackRock Fund Advisors |
83,962 |
251,000 |
0.82% |
|
|
| 13 |
Yellowstone Partners, LLC |
43,600 |
130,000 |
0.42% |
|
|
| 14 |
NORTHERN TRUST CORP |
32,214 |
96,000 |
0.31% |
|
|
| 15 |
MORGAN STANLEY |
26,609 |
80,000 |
0.26% |
|
|
| 16 |
Evanson Asset Management, LLC |
20,000 |
60,000 |
0.20% |
|
|
| 17 |
NOMURA HOLDINGS INC |
12,700 |
36,000 |
0.12% |
|
|
| 18 |
CITADEL ADVISORS LLC |
10,677 |
32,000 |
0.10% |
|
|
| 19 |
BLACKROCK ADVISORS LLC |
6,152 |
18,000 |
0.06% |
|
|
| 20 |
BlackRock Investment Management, LLC |
5,815 |
17,000 |
0.06% |
|
|
| 21 |
UBS Group AG |
2,222 |
7,000 |
0.02% |
|
|
| 22 |
Walleye Trading LLC |
1,600 |
5,000 |
0.02% |
|
|
| 23 |
ADVISOR GROUP, INC. |
2,000 |
5,000 |
0.02% |
|
|
| 24 |
JPMORGAN CHASE & CO |
1,000 |
3,000 |
0.01% |
|
|
| 25 |
WOLVERINE TRADING LP /BD |
666 |
1,998 |
0.01% |
|
|
| 26 |
BANK OF AMERICA CORP /DE/ |
2 |
0 |
0.00% |
|
|
