| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | QVT Financial LP | 75,000,000 | 1,739,250,000 | 66.89% | ||
| 2 | FMR LLC | 7,235,632 | 167,794,000 | 6.45% | ||
| 3 | Capital Research Global Investors | 3,453,800 | 80,094,000 | 3.08% | ||
| 4 | PRIMECAP MANAGEMENT CO/CA/ | 3,337,202 | 77,390,000 | 2.98% | ||
| 5 | PRICE T ROWE ASSOCIATES INC /MD/ | 2,879,898 | 66,785,000 | 2.57% | ||
| 6 | JANUS HENDERSON GROUP PLC | 2,063,549 | 47,854,000 | 1.84% | ||
| 7 | D. E. Shaw & Co., Inc. | 1,687,335 | 39,129,000 | 1.50% | ||
| 8 | FRANKLIN RESOURCES INC | 1,463,582 | 33,940,000 | 1.31% | ||
| 9 | BlackRock Finance, Inc. | 1,300,567 | 30,160,000 | 1.16% | ||
| 10 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,055,700 | 24,482,000 | 0.94% | Call | |
| 11 | Camber Capital Management LP | 1,000,000 | 23,190,000 | 0.89% | ||
| 12 | JPMORGAN CHASE & CO | 923,649 | 21,419,000 | 0.82% | ||
| 13 | DLD ASSET MANAGEMENT, LP | 807,600 | 18,729,000 | 0.72% | Call | |
| 14 | IPL ADVISERS, LLC | 770,947 | 17,878,000 | 0.69% | ||
| 15 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 726,400 | 16,845,000 | 0.65% | Put | |
| 16 | PERCEPTIVE ADVISORS LLC | 572,700 | 13,281,000 | 0.51% | ||
| 17 | STATE STREET CORP | 546,920 | 12,682,000 | 0.49% | ||
| 18 | Blackstone Inc. | 353,669 | 8,202,000 | 0.32% | ||
| 19 | Tourbillon Capital Partners, L.P. | 352,700 | 8,179,000 | 0.31% | ||
| 20 | PointState Capital LP | 350,200 | 8,121,000 | 0.31% | ||
| 21 | NORTHERN TRUST CORP | 322,685 | 7,482,000 | 0.29% | ||
| 22 | VHCP MANAGEMENT II, LLC | 301,718 | 6,997,000 | 0.27% | ||
| 23 | CITADEL ADVISORS LLC | 301,474 | 6,991,000 | 0.27% | ||
| 24 | PERCEPTIVE ADVISORS LLC | 300,000 | 6,957,000 | 0.27% | Call | |
| 25 | Invesco Ltd. | 275,992 | 6,400,000 | 0.25% | ||
| 26 | DEERFIELD MANAGEMENT COMPANY, L.P. | 239,180 | 5,547,000 | 0.21% | ||
| 27 | CITIGROUP INC | 222,288 | 5,155,000 | 0.20% | ||
| 28 | Ghost Tree Capital, LLC | 175,000 | 4,058,000 | 0.16% | ||
| 29 | Artal Group S.A. | 175,000 | 4,058,000 | 0.16% | ||
| 30 | AMERICAN FINANCIAL GROUP INC | 172,395 | 3,998,000 | 0.15% | ||
| 31 | VANGUARD GROUP INC | 171,428 | 3,976,000 | 0.15% | ||
| 32 | MILLENNIUM MANAGEMENT LLC | 160,580 | 3,724,000 | 0.14% | ||
| 33 | C WorldWide Group Holding A/S | 131,500 | 3,049,000 | 0.12% | ||
| 34 | Rock Springs Capital Management LP | 125,000 | 2,899,000 | 0.11% | ||
| 35 | DRIEHAUS CAPITAL MANAGEMENT LLC | 117,534 | 2,726,000 | 0.10% | ||
| 36 | DEUTSCHE BANK AG\ | 103,688 | 2,404,000 | 0.09% | ||
| 37 | Bank of New York Mellon Corp | 102,664 | 2,380,000 | 0.09% | ||
| 38 | Ratan Capital Management LP | 100,000 | 2,319,000 | 0.09% | ||
| 39 | MILLENNIUM MANAGEMENT LLC | 100,000 | 2,319,000 | 0.09% | Call | |
| 40 | ALPS ADVISORS INC | 95,593 | 2,217,000 | 0.09% | ||
| 41 | MORGAN STANLEY | 94,093 | 2,182,000 | 0.08% | ||
| 42 | Candriam S.C.A. | 93,000 | 2,157,000 | 0.08% | ||
| 43 | OXFORD ASSET MANAGEMENT LLP | 92,329 | 2,141,000 | 0.08% | ||
| 44 | GOLDMAN SACHS GROUP INC | 92,220 | 2,139,000 | 0.08% | ||
| 45 | BARCLAYS PLC | 83,675 | 1,941,000 | 0.07% | ||
| 46 | TIAA CREF INVESTMENT MANAGEMENT LLC | 82,671 | 1,917,000 | 0.07% | ||
| 47 | Avoro Capital Advisors LLC | 82,087 | 1,904,000 | 0.07% | ||
| 48 | PRUDENTIAL FINANCIAL INC | 80,170 | 1,859,000 | 0.07% | ||
| 49 | CITADEL ADVISORS LLC | 70,400 | 1,633,000 | 0.06% | Call | |
| 50 | Atika Capital Management LLC | 70,000 | 1,624,000 | 0.06% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
