| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ROYAL BANK OF CANADA | 200 | 3,000 | 0.01% | ||
| 2 | WELLS FARGO & COMPANY/MN | 1,000 | 13,000 | 0.03% | ||
| 3 | Tower Research Capital LLC (TRC) | 1,453 | 19,000 | 0.04% | ||
| 4 | MORGAN STANLEY | 5,511 | 72,000 | 0.15% | ||
| 5 | SABBY MANAGEMENT, LLC | 40,000 | 524,000 | 1.08% | ||
| 6 | Cormorant Asset Management, LP | 50,000 | 655,000 | 1.35% | ||
| 7 | Foresite Capital Management II, LLC | 80,883 | 1,059,000 | 2.18% | ||
| 8 | SPHERA FUNDS MANAGEMENT LTD. | 196,800 | 2,576,000 | 5.30% | ||
| 9 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 197,300 | 2,583,000 | 5.31% | ||
| 10 | FRANKLIN RESOURCES INC | 202,279 | 2,648,000 | 5.45% | ||
| 11 | DEERFIELD MANAGEMENT COMPANY, L.P. | 219,558 | 2,874,000 | 5.91% | ||
| 12 | Versant Venture Management, LLC | 268,672 | 3,516,916 | 7.24% | ||
| 13 | ORBIMED ADVISORS LLC | 268,672 | 3,517,000 | 7.24% | ||
| 14 | FMR LLC | 925,000 | 12,108,000 | 24.91% | ||
| 15 | BAUPOST GROUP LLC/MA | 1,256,006 | 16,441,000 | 33.82% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.