| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | SPDR S&P 500 ETF TR PUT | 16,250 | 306,773,000 | 12.64% | Put | |
| 2 | ISHARES TR | 25,500 | 273,123,000 | 11.25% | Put | |
| 3 | ELI LILLY & CO | 21,855 | 182,904,000 | 7.54% | Call | |
| 4 | GILEAD SCIENCES INC | 9,896 | 97,169,000 | 4.00% | Call | |
| 5 | BIOGEN INC | 3,090 | 90,169,000 | 3.71% | Call | |
| 6 | GILEAD SCIENCES INC | 4,973 | 48,830,000 | 2.01% | Put | |
| 7 | MEDICINES CO | 11,749 | 44,599,000 | 1.84% | Call | |
| 8 | ZOGENIX INC | 31,115 | 42,005,000 | 1.73% | Call | |
| 9 | BIOGEN INC | 1,419 | 41,408,000 | 1.71% | Put | |
| 10 | ABBVIE INC | 7,456 | 40,568,000 | 1.67% | Call | |
| 11 | ISHARES TR | 327,168 | 35,727,000 | 1.47% | ||
| 12 | EDWARDS LIFESCIENCES CORP | 1,682 | 34,896,000 | 1.44% | Put | |
| 13 | BIOMARIN PHARMACEUTICAL INC | 2,911 | 30,659,000 | 1.26% | Put | |
| 14 | TENET HEALTHCARE CORP | 7,745 | 28,595,000 | 1.18% | Call | |
| 15 | BIOMARIN PHARMACEUTICAL INC CALL | 2,375 | 25,014,000 | 1.03% | Call | |
| 16 | GW PHARMACEUTICALS PLC | 2,712 | 24,780,000 | 1.02% | Put | |
| 17 | Mobileye NV | 5,158 | 23,459,000 | 0.97% | Put | |
| 18 | MYLAN N V | 5,756 | 23,174,000 | 0.95% | Put | |
| 19 | BIOGEN INC | 78,629 | 22,945,000 | 0.95% | ||
| 20 | SAREPTA THERAPEUTICS INC CALL | 6,671 | 21,421,000 | 0.88% | Call | |
| 21 | ELI LILLY & CO | 2,438 | 20,404,000 | 0.84% | Put | |
| 22 | SPDR S&P BIOTECH ETF | 3,144 | 19,571,000 | 0.81% | Put | |
| 23 | BIOMARIN | 174,073 | 18,333,000 | 0.76% | ||
| 24 | BRISTOL MYERS SQUIBB CO | 3,073 | 18,192,000 | 0.75% | Call | |
| 25 | ALEXION PHARMACEUTICALS INC | 975 | 15,248,000 | 0.63% | Put | |
| 26 | MYLAN N V | 376,827 | 15,171,000 | 0.63% | ||
| 27 | PIONEER NAT RES CO | 123,600 | 15,035,000 | 0.62% | ||
| 28 | PIONEER NAT RES CO | 1,236 | 15,035,000 | 0.62% | Put | |
| 29 | GLOBAL BLOOD THERAPEUTICS IN COM | 342,857 | 14,455,000 | 0.60% | ||
| 30 | ALNYLAM PHARMACEUTICALS INC | 1,676 | 13,468,000 | 0.55% | Call | |
| 31 | NewLink Genetics Corp | 3,701 | 13,264,000 | 0.55% | Call | |
| 32 | ABBVIE INC | 2,272 | 12,362,000 | 0.51% | Put | |
| 33 | CALL APPLE INC $110 EXP 01/20/17 AAPL 170120C00110000 | 1,110 | 12,243,000 | 0.50% | Call | |
| 34 | UNITED THERAPEUTICS CORP | 918 | 12,048,000 | 0.50% | Call | |
| 35 | INTEROIL CORP | 3,356 | 11,313,000 | 0.47% | Put | |
| 36 | INTEROIL CORP | 328,705 | 11,081,000 | 0.46% | ||
| 37 | EDWARDS LIFESCIENCES CORP | 77,255 | 10,983,000 | 0.45% | ||
| 38 | TENET HEALTHCARE CORP | 2,907 | 10,733,000 | 0.44% | Put | |
| 39 | MOBILEYE N V AMSTELVEEN | 235,819 | 10,725,000 | 0.44% | ||
| 40 | HERON THERAPEUTICS INC | 4,223 | 10,304,000 | 0.42% | Call | |
| 41 | CEMPRA INC | 3,649 | 10,159,000 | 0.42% | Call | |
| 42 | KITE PHARMA INC | 1,823 | 10,150,000 | 0.42% | Put | |
| 43 | MANNKIND CORP | 30,930 | 9,929,000 | 0.41% | Call | |
| 44 | GEVO INC | 100,000 | 9,819,000 | 0.40% | ||
| 45 | TENET HEALTHCARE CORP | 245,938 | 9,080,000 | 0.37% | ||
| 46 | ACORDA THERAPEUTICS INC | 9,600,000 | 8,664,000 | 0.36% | ||
| 47 | AGIOS PHARMACEUTICALS INC | 1,173 | 8,280,000 | 0.34% | Put | |
| 48 | REGULUS THERAPEUTICS INC | 12,127 | 7,931,000 | 0.33% | Call | |
| 49 | TENAX THERAPEUTICS INC COM | 2,604,660 | 7,892,000 | 0.33% | ||
| 50 | AGIOS PHARMACEUTICALS INC | 109,521 | 7,731,000 | 0.32% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-15-065626, filed 2015.11.16).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
