| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Novo Holdings A/S | 1,280,185 | 8,859,000 | 42.91% | ||
| 2 | FMR LLC | 673,461 | 4,660,000 | 22.57% | ||
| 3 | PUTNAM INVESTMENTS LLC | 551,240 | 3,815,000 | 18.48% | ||
| 4 | Cormorant Asset Management, LP | 203,464 | 1,408,000 | 6.82% | ||
| 5 | VANGUARD GROUP INC | 97,393 | 674,000 | 3.26% | ||
| 6 | STATE STREET CORP | 49,800 | 345,000 | 1.67% | ||
| 7 | Granahan Investment Management, LLC | 33,010 | 228,000 | 1.10% | ||
| 8 | TWO SIGMA SECURITIES, LLC | 21,608 | 150,000 | 0.73% | ||
| 9 | GEODE CAPITAL MANAGEMENT, LLC | 19,859 | 137,000 | 0.66% | ||
| 10 | UBS Group AG | 19,773 | 137,000 | 0.66% | ||
| 11 | RENAISSANCE TECHNOLOGIES LLC | 10,900 | 75,000 | 0.36% | ||
| 12 | Truepoint, Inc. | 10,000 | 69,000 | 0.33% | ||
| 13 | SONORA INVESTMENT MANAGEMENT, LLC | 3,500 | 24,220 | 0.12% | ||
| 14 | BARCLAYS PLC | 2,700 | 19,000 | 0.09% | ||
| 15 | BlackRock Finance, Inc. | 2,145 | 15,000 | 0.07% | ||
| 16 | Ironwood Financial, llc | 1,475 | 10,000 | 0.05% | ||
| 17 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 1,507 | 10,000 | 0.05% | ||
| 18 | Tower Research Capital LLC (TRC) | 600 | 4,000 | 0.02% | ||
| 19 | TCI Wealth Advisors, Inc. | 400 | 3,000 | 0.01% | ||
| 20 | ACROSPIRE INVESTMENT MANAGEMENT LLC | 100 | 1,000 | 0.00% | ||
| 21 | DEUTSCHE BANK AG\ | 100 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
