| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | NEA Management Company, LLC | 1,460,209 | 4,235,000 | 32.60% | ||
| 2 | FRANKLIN RESOURCES INC | 1,216,840 | 3,529,000 | 27.17% | ||
| 3 | Tekla Capital Management LLC | 811,227 | 2,353,000 | 18.11% | ||
| 4 | RA CAPITAL MANAGEMENT, L.P. | 562,693 | 1,632,000 | 12.56% | ||
| 5 | ROYCE & ASSOCIATES LP | 152,733 | 443,000 | 3.41% | ||
| 6 | VANGUARD GROUP INC | 121,657 | 353,000 | 2.72% | ||
| 7 | PANAGORA ASSET MANAGEMENT INC | 77,408 | 224,000 | 1.72% | ||
| 8 | DEUTSCHE BANK AG\ | 37,711 | 109,000 | 0.84% | ||
| 9 | BlackRock Fund Advisors | 13,021 | 38,000 | 0.29% | ||
| 10 | GOLDMAN SACHS GROUP INC | 11,092 | 32,000 | 0.25% | ||
| 11 | Cambridge Investment Research Advisors, Inc. | 10,452 | 30,000 | 0.23% | ||
| 12 | UBS Group AG | 1,485 | 4,000 | 0.03% | ||
| 13 | BlackRock Investment Management, LLC | 1,046 | 3,000 | 0.02% | ||
| 14 | BANK OF AMERICA CORP /DE/ | 662 | 2,000 | 0.02% | ||
| 15 | Tower Research Capital LLC (TRC) | 220 | 1,000 | 0.01% | ||
| 16 | Walleye Trading LLC | 300 | 1,000 | 0.01% | ||
| 17 | Camarda Financial Advisors, LLC | 200 | 1,000 | 0.01% | ||
| 18 | WOLVERINE TRADING LP /BD | 66 | 198 | 0.00% | ||
| 19 | Creative Planning | 149 | 0 | 0.00% | ||
| 20 | WELLS FARGO & COMPANY/MN | 142 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
