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Institutional Investment Manager
RA CAPITAL MANAGEMENT, L.P.
RA CAPITAL MANAGEMENT, L.P. (CIK: 0001346824) incorporated in Delaware, located at 200 Berkeley Street, 18th Floor, Boston, MA. Institutional holdings reported to the SEC.

Institutional Holdings (2016Q2)
Portfolio Summary: 32 holdings with a total value of $722,235,000.
#
Name
Shares
Value ($)
%
Options
Notes
1 WAVE LIFE SCIENCES LTD 7,088,651 146,664,000 20.31%
2 ACHILLION PHARMACEUTICALS INC COM 12,033,220 93,859,000 13.00%
3 AXOVANT SCIENCES LTD 5,000,000 64,200,000 8.89%
4 AVEXIS INC COM 1,339,382 50,923,000 7.05%
5 ACLARIS THERAPEUTICS INC COM 2,627,719 48,534,000 6.72%
6 NEKTAR THERAPEUTICS COM 3,224,854 45,890,000 6.35%
7 Ascendis Pharma 3,412,857 45,289,000 6.27%
8 TG THERAPEUTICS INC COM 4,531,714 27,462,000 3.80%
9 ARDELYX INC COM 2,312,243 20,186,000 2.79%
10 ZOGENIX INC 2,451,237 19,732,000 2.73%
11 VITAE PHARMACEUTICALS INC 1,575,000 16,994,000 2.35%
12 AIMMUNE THERAPEUTICS INC COM 1,292,940 13,990,000 1.94%
13 ALCOBRA LTD 3,032,911 13,618,000 1.89%
14 Proteon Therapeutics 1,626,931 13,064,000 1.81%
15 Aquinox Pharmaceuticals Inc 1,691,977 11,201,000 1.55%
16 Strongbridge Biopharma plc 2,675,338 10,648,000 1.47%
17 NATERA INC 783,520 9,453,000 1.31%
18 DIMENSION THERAPEUTICS INC COM 1,548,033 9,288,000 1.29%
19 BIOCRYST PHARMACEUTICALS 2,989,795 8,491,000 1.18%
20 Dicerna Pharmaceuticals 2,428,571 7,286,000 1.01%
21 SANGAMO BIOSCIENCES INCORPORATED 1,165,938 6,751,000 0.93%
22 Agile Therapeutics, Inc. 853,151 6,492,000 0.90%
23 TENAX THERAPEUTICS INC COM 2,389,700 6,118,000 0.85%
24 EIGER BIOPHARMACEUTICALS INC 291,700 5,781,000 0.80%
25 BEIGENE LTD 170,000 5,066,000 0.70%
26 CIDARA THERAPEUTICS INC 410,809 4,235,000 0.59%
27 AKARI THERAPEUTICS PLC 234,240 3,160,000 0.44%
28 AEGLEA BIOTHERAPEUTICS INC COM 521,550 2,535,000 0.35%
29 MERUS N V 237,599 1,898,000 0.26%
30 ZYNERBA PHARMACEUTICALS INC 253,468 1,736,000 0.24%
31 ARCA BIOPHARMA INCORPORATED COM PAR .001 562,693 1,632,000 0.23%
32 ProNAi Therapeutics, Inc. 29,719 59,000 0.01%

Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-16-119492, filed 2016.08.15).

From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.