| 1 |
ORBIMED ADVISORS LLC |
9,127,990 |
41,259,000 |
35.61% |
|
|
| 2 |
FMR LLC |
7,989,923 |
36,162,000 |
31.21% |
|
|
| 3 |
Aisling Capital LLC |
7,480,887 |
33,814,000 |
29.19% |
|
|
| 4 |
VANGUARD GROUP INC |
393,121 |
1,777,000 |
1.53% |
|
|
| 5 |
BlackRock Fund Advisors |
185,736 |
840,000 |
0.73% |
|
|
| 6 |
NORTHERN TRUST CORP |
61,099 |
276,000 |
0.24% |
|
|
| 7 |
CARL DOMINO INC |
60,036 |
275,000 |
0.24% |
|
|
| 8 |
GEODE CAPITAL MANAGEMENT, LLC |
57,281 |
258,000 |
0.22% |
|
|
| 9 |
BUCKINGHAM STRATEGIC WEALTH, LLC |
50,000 |
226,000 |
0.20% |
|
|
| 10 |
BlackRock Institutional Trust Company, N.A. |
39,289 |
178,000 |
0.15% |
|
|
| 11 |
GOLDMAN SACHS GROUP INC |
34,484 |
156,000 |
0.13% |
|
|
| 12 |
MILLENNIUM MANAGEMENT LLC |
29,114 |
132,000 |
0.11% |
|
|
| 13 |
Sequoia Financial Advisors, LLC |
20,000 |
90,000 |
0.08% |
|
|
| 14 |
RHUMBLINE ADVISERS |
15,533 |
70,000 |
0.06% |
|
|
| 15 |
NEW YORK STATE COMMON RETIREMENT FUND |
13,932 |
63,000 |
0.05% |
|
|
| 16 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
13,819 |
62,000 |
0.05% |
|
|
| 17 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
12,781 |
58,000 |
0.05% |
|
|
| 18 |
Bank of New York Mellon Corp |
10,558 |
47,000 |
0.04% |
|
|
| 19 |
TEACHERS ADVISORS, LLC |
6,996 |
32,000 |
0.03% |
|
|
| 20 |
BlackRock Investment Management, LLC |
5,969 |
27,000 |
0.02% |
|
|
| 21 |
AMERICAN INTERNATIONAL GROUP, INC. |
3,826 |
17,294 |
0.01% |
|
|
| 22 |
BLACKROCK ADVISORS LLC |
2,026 |
9,000 |
0.01% |
|
|
| 23 |
Nationwide Fund Advisors |
1,754 |
8,000 |
0.01% |
|
|
| 24 |
MORGAN STANLEY |
1,217 |
6,000 |
0.01% |
|
|
| 25 |
DEUTSCHE BANK AG\ |
1,242 |
4,000 |
0.00% |
|
|
| 26 |
Tower Research Capital LLC (TRC) |
829 |
4,000 |
0.00% |
|
|
| 27 |
BNP PARIBAS FINANCIAL MARKETS |
452 |
2,043 |
0.00% |
|
|
| 28 |
CITIGROUP INC |
545 |
2,000 |
0.00% |
|
|
| 29 |
BANK OF AMERICA CORP /DE/ |
545 |
2,000 |
0.00% |
|
|
| 30 |
BARCLAYS PLC |
83 |
0 |
0.00% |
|
|
| 31 |
STRS OHIO |
0 |
0 |
0.00% |
|
|
