| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | ACUTA CAPITAL PARTNERS, LLC | 247,956 | 5,279,000 | 1.78% | ||
| 52 | VANGUARD GROUP INC | 270,253 | 5,753,000 | 1.94% | ||
| 53 | Ghost Tree Capital, LLC | 300,000 | 6,387,000 | 2.15% | ||
| 54 | BlackRock Finance, Inc. | 345,041 | 7,346,000 | 2.47% | ||
| 55 | FRANKLIN RESOURCES INC | 366,000 | 7,792,000 | 2.62% | ||
| 56 | VHCP MANAGEMENT II, LLC | 725,029 | 15,436,000 | 5.20% | ||
| 57 | Rock Springs Capital Management LP | 788,959 | 16,797,000 | 5.66% | ||
| 58 | RA CAPITAL MANAGEMENT, L.P. | 1,351,808 | 28,780,000 | 9.69% | ||
| 59 | WELLINGTON MANAGEMENT GROUP LLP | 1,631,429 | 34,733,000 | 11.70% | ||
| 60 | Novo Holdings A/S | 2,031,562 | 43,252,000 | 14.56% | ||
| 61 | NEA Management Company, LLC | 3,493,636 | 74,380,000 | 25.04% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.