| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Novo Holdings A/S | 2,901,927 | 21,358,000 | 39.50% | ||
| 2 | SV Health Investors, LLC | 2,579,490 | 18,985,000 | 35.11% | ||
| 3 | RA CAPITAL MANAGEMENT, L.P. | 591,070 | 4,350,000 | 8.04% | ||
| 4 | INTERWEST VENTURE MANAGEMENT CO | 329,942 | 2,428,000 | 4.49% | ||
| 5 | INTERNATIONAL BIOTECHNOLOGY TRUST PLC | 322,436 | 2,276,000 | 4.21% | ||
| 6 | VHCP MANAGEMENT II, LLC | 221,651 | 1,631,000 | 3.02% | ||
| 7 | EVENTIDE ASSET MANAGEMENT, LLC | 189,900 | 1,367,000 | 2.53% | ||
| 8 | VANGUARD GROUP INC | 180,872 | 1,303,000 | 2.41% | ||
| 9 | BOOTHBAY FUND MANAGEMENT, LLC | 21,665 | 159,000 | 0.29% | ||
| 10 | Alyeska Investment Group, L.P. | 10,984 | 81,000 | 0.15% | ||
| 11 | FIRST QUADRANT LLC/CA | 10,850 | 80,000 | 0.15% | ||
| 12 | BlackRock Finance, Inc. | 4,331 | 32,000 | 0.06% | ||
| 13 | UBS Group AG | 1,506 | 11,000 | 0.02% | ||
| 14 | Tower Research Capital LLC (TRC) | 905 | 7,000 | 0.01% | ||
| 15 | PANAGORA ASSET MANAGEMENT INC | 608 | 4,000 | 0.01% | ||
| 16 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 306 | 3,000 | 0.01% | ||
| 17 | MORGAN STANLEY | 200 | 1,000 | 0.00% | ||
| 18 | DEUTSCHE BANK AG\ | 5 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.