| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Novo Holdings A/S | 2,901,927 | 20,517,000 | 39.84% | ||
| 2 | SV Health Investors, LLC | 2,579,490 | 18,237,000 | 35.41% | ||
| 3 | RA CAPITAL MANAGEMENT, L.P. | 591,070 | 4,179,000 | 8.12% | ||
| 4 | INTERWEST VENTURE MANAGEMENT CO | 329,942 | 2,333,000 | 4.53% | ||
| 5 | INTERNATIONAL BIOTECHNOLOGY TRUST PLC | 322,436 | 2,186,000 | 4.24% | ||
| 6 | VIVO CAPITAL, LLC | 300,325 | 2,123,000 | 4.12% | ||
| 7 | VHCP MANAGEMENT II, LLC | 221,651 | 1,322,000 | 2.57% | ||
| 8 | VANGUARD GROUP INC | 39,296 | 278,000 | 0.54% | ||
| 9 | BOOTHBAY FUND MANAGEMENT, LLC | 16,346 | 116,000 | 0.23% | ||
| 10 | FIRST QUADRANT LLC/CA | 12,750 | 90,000 | 0.17% | ||
| 11 | Alyeska Investment Group, L.P. | 11,483 | 81,000 | 0.16% | ||
| 12 | BlackRock Fund Advisors | 2,274 | 16,000 | 0.03% | ||
| 13 | UBS Group AG | 909 | 6,000 | 0.01% | ||
| 14 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 310 | 3,000 | 0.01% | ||
| 15 | BlackRock Institutional Trust Company, N.A. | 362 | 3,000 | 0.01% | ||
| 16 | BLACKROCK ADVISORS LLC | 258 | 2,000 | 0.00% | ||
| 17 | Tower Research Capital LLC (TRC) | 263 | 2,000 | 0.00% | ||
| 18 | MORGAN STANLEY | 200 | 1,000 | 0.00% | ||
| 19 | Creative Planning | 142 | 1,000 | 0.00% | ||
| 20 | DEUTSCHE BANK AG\ | 5 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
